| Japanese |
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| Title | 多核種 (Na131I, 99mTcO4-, 201TlCl) Scintigraphyによる甲状腺疾患の質的診断 |
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| Subtitle | 原著 |
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| Authors | 熊野町子*, 楢林和之*, 伊藤一夫** |
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| Organization | *兵庫県立病院がんセンター放射線科, **神戸大学医学部放射線医学教室 |
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| Journal | 核医学 |
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| Volume | 15 |
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| Number | 5 |
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| Page | 713-720 |
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| Year/Month | 1978/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」甲状腺疾患の非観血的診断法としてNa131Iや99mTcO4-によるRI検査が汎用されている. しかし, 一核種のみのScintigramでは病巣の正確な把握が困難なことが多く, またこれら二核種を用いても, 疾患によっては解離現象が出現して, やはり診断しえないことがある. そのような場合に, 201TlClによるScintigramを追加すると, 病巣の質的診断がより正確になり得ることが判明した. すなわち, Na131Iと99mTcO4-で欠損像を示し, 201TlClが集積像を示す病巣は充実性腫瘍であり, 特に201TlClの集積が著しい時は濾胞腺腫や濾胞癌のことが多い. その際99mTcO4-の欠損がNa131Iの欠損より大きく描画されると, 濾胞癌が考えられる. Na131Iで欠損し99MTcO4-と201TlClが集積する場合はその病巣の悪性化を考慮する必要がある. 3核種とも集積しない病巣は良性嚢胞性病巣である. また201TlClは転移巣の検索に有用である. 以上のごとく, 甲状腺Scintigraphyでは多核種の適当な組合せが必要である. |
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| Practice | 臨床医学：一般 |
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| Keywords | Na131I, 201TlCl, 99mTcO4-, Thyroid Scintigram, Thyroid Tumor |
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| English |
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| Title | Differential Diagnosis of Thyroid Diseases Using Na131I, 99mTcO4- and 201TlCl Scintigraphy |
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| Subtitle | Original Articles |
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| Authors | Machiko KUMANO*, Kazuyuki NARABAYASHI*, Kazuo ITO** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Hyogo Cancer Hospital, **Department of Radiology, Kobe University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 15 |
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| Number | 5 |
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| Page | 713-720 |
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| Year/Month | 1978/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] In thyroid scintigraphy it is preferable to use an adequate combination of various radionuclides to determine the diagnosis. Scanning with use single radionuclide is unable to achieve the accurate diagnosis. Even usage of double radionuclides results in dissociation in the interpretation of the images. We proved that the use of triple radionuclides such as Na131I, 99mTcO- and 201TlCl generally yielded the most informative scintigram for the evaluation of the lesions. In the case of the nodules which is cold with both Na131I and 99mTcO- and hot with 201TlCl, the lesions were proved to be solid tumors such as chronic thyroiditis, adenomatous goiter, follicular adenoma and carcinoma. Further examination showed that the high rate of uptake of 201TlCl into the nodule gave positive identification of follicular adenoma and carcinoma. The additional finding was that the greater cold areas with 99mTcO4- than that with Na131I indicated the high probability of the follicular carcinoma. The nodule which is cold with Na131I and hot with both 99mTcO4- and 201TlCl should be considered malignant tumors. With use of 201TlCl the high incidence of hot scan was seen in the both primary and metastatic lesion of thyroid cancer, especially in the well differentiated follicular carcinoma, therefore 201TlCl was advantageous to evaluate the metastatic tumors in the neck. 201TlCl as well as Na131I and 99mTcO4- do not concentrate in the benign cystic lesions. |
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| Practice | Clinical medicine |
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| Keywords | Na131I, 201TlCl, 99mTcO4-, Thyroid Scintigram, Thyroid Tumor |
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