Japanese
Title脈絡叢への99mTcO4-集積に対するPerchlorate投与の影響の定量的検討
Subtitle原著
Authors川口新一郎*, 飯尾正宏*, 村田啓*, 千葉一夫*, 山田英夫*, 松井謙吾*, 戸張千年*, 丹野宗彦*, 星賢二*, 藤原敬悟**, 星豊**, 布施正明**
Authors(kana)
Organization*東京都養育院付属病院核医学放射線部, **東京都養育院付属病院脳神経外科
Journal核医学
Volume15
Number5
Page661-669
Year/Month1978/8
Article原著
Publisher日本核医学会
Abstract「要旨」99mTcO4-で脳スキャンを行なう時, 脈絡叢への99mTcO4-の集積をブロックするために通常perchlorateの前投与が行なわれている. 著者らは投与するperchlorateの最小有効量および投与してから99mTcO4-を静注するまでの最適間隔を検討した. 都養育院付属病院で1976年7月以来脳スキャンを行なった内の278例を対象とした. 投与するperchlorateの量は0〜600mg, 投与と99mTcO4-を静注するまでの間隔は1〜330分の種々の条件下で検討した. 1) perchlorateを投与しなかった時脈絡叢は82%が陽性, 14%が疑陽性, 4%が陰性であった. 2) 投与されるperchlorateの最小有効量は200mgであった. その時脈絡叢は2%が陽性, 38%が疑陽性, 60%が陰性であった. perchlorateと99mTcO4-を静注するまでの最適間隔は60〜120分であった.
Practice臨床医学：一般
KeywordsChoroid plexus, Brain scan, Perchlorate, KClO4.
English
TitleQuantitative Evaluation of the Effect of Potassium Perchlorate Administration on the uptake of 99mTcO4- by Choroid Plexus
SubtitleOriginal Articles
AuthorsShinichiro KAWAGUCHI, Masahiro IIO, Hajime MURATA, Kazuo CHIBA, Hideo YAMADA, Kengo MATSUI, Chitose TOBARI, Munehiko TANNO, Kenji HOSHI, Keigo FUJIWARA*, Yutaka HOSHI*, Masaaki FUSE*
Authors(kana)
OrganizationDepartment of Nuclear Medicine and Radiological Sciences, *Neurosurgery, Tokyo Metropolitan Geriatric Hospital
JournalThe Japanese Journal of nuclear medicine
Volume15
Number5
Page661-669
Year/Month1978/8
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Premedication of perchlorate is being performed in order to block the accumulation of 99mTcO4- into choroid plexus during brain scan by 99mTcO4-. The optimal dose of perchlorate and optimal interval between perchlorate administration and 99mTcO4- injection were studied in this report. Two hundred and seventy eight brain scans by 99mTcO4- were evaluated for this purpose during the period of a year from July 1976 to July 1977 in Tokyo Metropolitan Geriatric Hospital. Various doses of potassium (0 - 600 mg) were orally given and various time intervals were taken before 99mTcO4- injection. The results were as follows : 1) When oral premedication of potassium perchlorate was not performed the visualization of choroid plexus was observed as positive in 82%, suspicious in 14% and negative in 4% in the brain scan by 99mTcO4-. 2) In order to block the accumulation of 99mTcO4- into choroid plexus more than 200 mg dose of potassium perchlorate was found to be necessary to administrate. In the oral dose of 200 mg potassium perchlorate the visualization of chroid plexus was noted positive in 2%, suspicious in 38% and negative in 60%. The potimal time interval between perchlorate administration and 99mTcO4- injection was 60 - 120 minutes.
PracticeClinical medicine
KeywordsChoroid plexus, Brain scan, Perchlorate, KClO4.

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