Japanese
Title多発性骨髄腫10例における99mTc-diphosphonateによる骨スキャン所見の検討
Subtitle原著
Authors小泉潔*, 利波紀久*, 久田欣一*
Authors(kana)
Organization*金沢大学医学部核医学診療科
Journal核医学
Volume15
Number4
Page553-559
Year/Month1978/6
Article原著
Publisher日本核医学会
Abstract「要旨」10例の多発性骨髄腫の99mTc-EHDP骨スキャン所見を骨レ線所見と比較検討した. 全例において骨スキャン上何らかの異常を呈した. 骨スキャン異常としては, すべてがHot areaであって, 明らかなCold areaは認めなかった. 骨スキャン上異常所見を呈した部位は, 骨レ線上も必らず何らかの異常所見を呈したが, 逆に骨レ線上異常があっても骨スキャン上異常を認めない部位があった. 骨レ線上の病的骨折部位は, 骨スキャン上全例Hot areaを呈したが, Punched outの部位は骨スキヤン所見に乏しかった. 骨スキャン所見は血清アルカリフォスファターゼ値とある程度相関していた. 総じて骨レ線所見に比べ, 骨スキャン所見は乏しい結果を得たが, このことが多発性骨髄腫の骨病変の特徴であるように思われた.
Practice臨床医学:一般
KeywordsMultiple myeloma, Bone scan, 99mTc-diphosphonate
English
Title99mTc-Diphosphonate Bone Scanning in 10 Patients with Multiple Myeloma
SubtitleOriginal Article
AuthorsKiyoshi KOIZUMI, Norihisa TONAMI, Kinichi HISADA
Authors(kana)
OrganizationDepartment of Nuclear Medicine, School of Medicine, Kanazawa University
JournalThe Japanese Journal of nuclear medicine
Volume15
Number4
Page553-559
Year/Month1978/6
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]99mTc-diphosphonate bone scanning was performed in 10 patients with multiple myeloma, and compared with bone roentgenograms. In all of the cases, abnormal areas of increased activity were seen on bone scans, but cold area was not seen in any cases. The abnormal areas in the bone scans were also observed as the areas of abnormal findings in the roentgenograms. On the contrary, the abnormal areas in the roentgenograms were not always abnormal in the bone scans. Pathological fractures seen in the roentgenograms always showed the abnormal accumulations in the bone scans. But punched out lesions in the roentgenograms rarely showed scan abnormalities. The areas of bone destruction and loss of bone density in the roentgenograms showed either abnormal accumulations or normal accumulations in the bone scans. There were many abnormal areas seen on the bone scans in the case in which serum alkaline phosphatase was very high, and there were few abnormal areas seen on the bone scans in the cases in which serum alkaline phosphatase was normal value. However there were several cases in which serum alkaline phosphatase was relatively high, and did show few scan abnormalities. It is well known that bone scan is superior to roentgenogram in the detection of the bone metastasis from cancer. But in our study of multiple myeloma, there was a tendency that abnormal scan findings were lesser than those of roentgenograms. From this result, if we see a lesion of osteolysis in bone roentgenogram, bone scan may be of use to differentiate it to be multiple myeloma or bone metastasis from cancer.
PracticeClinical medicine
KeywordsMultiple myeloma, Bone scan, 99mTc-diphosphonate

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