Japanese
Title99mTcマイクロスフェアによる下肢静脈造影と肺シンチグラムの検討
Subtitle原著
Authors石井靖*, 浜中大三郎*, 鈴木輝康*, 米倉義晴*, 鳥塚莞爾*, 藤田透**, 熊田馨***
Authors(kana)
Organization*京都大学医学部放射線核医学科, **京都大学医学部附属病院中央放射線部, ***京都大学医学部第2外科
Journal核医学
Volume15
Number3
Page317-324
Year/Month1978/5
Article原著
Publisher日本核医学会
Abstract「要旨」下肢血栓症は, それに伴う肺栓塞症の主要な原因として, その的確な診断はとくに欧米においては, その頻度の高さから極めて重要視されている. 本邦においては, その頻度の点から比較的等閑視されてきたが, われわれは, その実態を調査する目的で99mTcマイクロスフェアによる放射性核種静脈造影法(RNV)と引き続いて得た肺シンチグラム所見とから, 下肢血栓症と肺栓塞症の存在診断をあわせて施行した. 血栓性静脈炎を主訴とするかまたはその既往を有する40名について検討したところ35例に下肢血栓の存在を認め, このうち9例(25.7%)に肺塞栓症の存在を認めた. 本症が本邦においても欧米と同様な頻度で肺栓塞症をきたすものであることが確められたが, 本法は非侵襲的かつ簡便に施行しうるので本邦においても本症が疑われる状況に際しては, ルチンに本法を施行し, より積極的な対応策を講じて肺栓塞症の予防に資するべきであると考えた.
Practice臨床医学：一般
Keywordsperipheral circulation, 99mTC-microsphere, radionuclide venography, pulmonary scintigrapy, thromboembolic disorder.
English
TitleCombined Detection for Pulmonary Embolism and Venous Thrombosis of Lower Extremity Using 99mTc Labeled Microsphere
SubtitleOriginal Articles
AuthorsY. ISHII*, D. HAMANAKA*, T. SUZUKI*, Y. YONEKURA*, T. FUJITA*, K. TORIZUKA*, K. KUMADA**
Authors(kana)
Organization*Department of Radiology and Nuclear Medicine, Kyoto University Medical School, **Department of Surgery, Kyoto University Medical School
JournalThe Japanese Journal of nuclear medicine
Volume15
Number3
Page317-324
Year/Month1978/5
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractIn western country, venous thrombosis of lower extremity has been important cause of pulmonary embolism and its incidence is quite high. On the other hand, the incidence of pulmonary embolism itself is though to be quite low in our country. Using capillary blockage for radionuclide venography(RNV)as well as lung scintigraphy, we attempted to investigate the relation between venous thrombosis and pulmonary embolism. Fourty patients with a symptom of swelling of the lower extremity were investigated. About 10mCi of diluted volume of 99mTc microsphere was introduced into dorsal vein, and standard RNV were taken concerning deep and superficial vein with or without application of tourniquet to the proximal site of ankle. Early dynamic images and late static images were taken, respectively, followed by the standard lung scintigraphy. Addition al inhalation scintigraphy was done later, if it was necessary to differentiate pulmonary embolism with other diseases with a perfusion defect. The criteria for the presence of venous thrombosis was as follows; 1)the presence of stenosis or defect with collateral circulation at the early dynamic images, and 2)the presence of hot spot formation at the late static images. A sole finding of the hot spot formation was evaluated to be false positive and twelve of seventeen cases with the hot spot at calf revealed to be false positive. According to this criteria, thirty five cases of all revealed positive findings, which located mostly in pelvic region and in popliteocalf region. Twelve of all cases revealed the pulmonary embolism, half of these have not any symptom suggestive of this disease, nine of these were with positive RNV findings and remainders were with false positive finding at calf region. In conclusion 25% of cases with venous thrombosis resulted in pulmonary embolism, which was the same incidence comparable with the reports in the western country. Hence, whenever indicative, combined RNV and lung scintigraphy for the detection of the thromboembolic disease should be necessary also in Japan.
PracticeClinical medicine
Keywordsperipheral circulation, 99mTC-microsphere, radionuclide venography, pulmonary scintigrapy, thromboembolic disorder.

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