| Japanese |
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| Title | 脳腫瘍診断におけるRIスキャンとCTの比較と併用 |
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| Subtitle | 原著 |
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| Authors | 平塚秀雄*, 岡田洽大*, 菅沼康雄*, 大畑正大*, 吉田麗己*, 武井秀憲*, 小松清秀*, 稲葉穰* |
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| Organization | *東京医科歯科大学医学部脳神経外科 |
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| Journal | 核医学 |
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| Volume | 15 |
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| Number | 2 |
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| Page | 197-205 |
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| Year/Month | 1978/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. はじめに」1948年Mooreが初めて放射性diiodofluoresceinを用いて脳腫瘍を診断して以来, 放射性同位元素(RI)による脳腫瘍の診断は, 特に脳神経外科領域には欠くことのできない, 重要な検査法としての地位を確立するに至った. しかしながら, 1973年Hounsfieldによって報告されたX-ray computed tomography(CT)は, その優れた診断力のため急速に普及し, わが国でも神経疾患診断の上に, 大きな変革をもたらしつつある. CTは特にnoninvasive brain imagingという点でRI brain scanと密接な関係にあり, CTの出現が, すでにroutine化されているRI-scanにあたえる影響は大きい. これら2方法の今後の診断上の問題点について, 特に "competitive or complementary" かについて, 両者の結果を比較検討しつつ考察を加えた. 「II. 症例および方法」症例は東京医科歯科大学脳神経外科学教室において昭和45年7月から昭和52年2月までの6年7カ月間に経験し, RI-scanを施行した脳腫瘍193例, 377回および昭和51年3月から昭和52年2月までの11カ月間に経験しCTを施行した脳腫瘍178例381回のうち, 両検査を施行した58例を中心として, 比較検討した. |
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| Practice | 臨床医学：一般 |
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| Keywords | Brain Tumors, Computed Tomography, Radioisotope Brain Scanning. |
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| English |
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| Title | Clinical Comparison Between Radioisotope Brain Scanning And Computed Tomography of Brain Tumors |
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| Subtitle | Original Articles |
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| Authors | Hideo HIRATSUKA, Kodai OKADA, Yasuo SUGANUMA, Masahiro OHATA, Hidenori TAKEI, Reiki YOSHIDA, Kiyohide KOMATSU, Yutaka INABA |
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| Organization | Depatment of Neurosurgery, School of Medicine, Tokyo Medical & Dental University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 15 |
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| Number | 2 |
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| Page | 197-205 |
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| Year/Month | 1978/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]The purpose of this paper is to compare the diagnostic value of radioisotope (RI) brain scanning and x-ray computed tomography (CT) in the evaluation of patients with brain tumor. Our study is based on 58 cases with brain tumor who were examined by both RI scans and CT. In RI imaging, overall positive rate was 91.7%, while in CT it was 100%. In radioisotope scanning with 99mTc-pertechnetate, five cases were falsely negative: low grade glioma 3, acoustic neurinoma 1 and pituitary adenoma 1. Improved brain scan images and specificity were obtained with combined use of different radioisotopes: 99mTC-pertechnetate, 99mTc-diphosphonate and 67Ga-citrate. Scans with 99mTc-diphosphonate are useful not only for detecting lesions of the skull, but also for differentiating tumor from infarction. Dynamic study by bolus injection of radioisotope and delayed scanning are essential for "nature" diagnosis of brain tumors. We emphasized usefulness of different informations from different isotopes. CT was very sensitive in detecting mass lesions with detailed morphological changes. Basically, CT displays the morphological pattern of the tumor and the brain more precisely, while radioisotope scanning defines tissue function or dynamic aspect. Future emphasis in nuclear medicine must be placed on the study of tumor specificity and dynamic aspect of the lesion rather than its structure, prospecting the development of more specific radiopharmaceuticals. Radioisotope scanning and CT are two noninvasive procedures that have a high rate of detection of intracranial tumors. From this comparative study, we conclude these two procedures are to be complementary in the investigation of intracranial tumors. |
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| Practice | Clinical medicine |
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| Keywords | Brain Tumors, Computed Tomography, Radioisotope Brain Scanning. |
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