Japanese
Title胸部疾患診断におけるDual Radioisotope Techniquesの応用
Subtitle原著
Authors藤井忠重*, 金井久容*, 小林俊夫*, 半田健次郎*, 草間昌三*, 矢野今朝人**, 滝沢正臣**
Authors(kana)
Organization*信州大学医学部第1内科, **信州大学医学部附属病院中央放射線部
Journal核医学
Volume15
Number1
Page49-55
Year/Month1978/2
Article原著
Publisher日本核医学会
Abstract「1. 緒言」RI像の解析においてRIの集積が正常か異常かの鑑別とその意味づけおよび解剖学的位置関係の把握は基本的な事項であり, 特に腫瘍シンチグラムの読影の際に問題になる. 著者らは肺癌診断の一環として197HgCl2の腫瘍シンチグラフィーを主体にして, 197HgCl2の集積の異常, 正常の鑑別および集積の意味づけを理解しやすくする目的で, 131I-RISAを併用するサブトラクション・シンチグラフィーを実施し, また197HgCl2の集積部の位置関係の判断を容易にし, 肺血流障害との関係を把握し, たがいのシンチグラムの意味づけを理解しやすくする目的で99mTc-MAAによる肺血流シンチグラフィーを併用するなど2核種を利用することで肺癌における核医学的診断能を, より向上すべく検討してきた. 今回は197HgCl2の腫瘍シンチグラフィーに肺血流シンチグラフィー, 血液プールシンチグラフィー, RI-アンジオグラフィーなどを併用し, さらに両者の画像を重ね合わせる方法も実施し, これら複数核種の同時利用法における臨床的意義につき検討した.
Practice臨床医学：一般
Keywords
English
TitleApplication of Dual Radioisotope Techniques for Diagnosis of Chest Diseases - Image Subtraction and Superimposition Methods Using 197HgCl2 and Other Radionuclides -
SubtitleOriginal Articles
AuthorsTadashige FUJII, Hisakata KANAI, Toshio KOBAYASHI, Kenjiro HANDA, Shozo KUSAMA, Kesato YANO*, Masaomi TAKIZAWA*
Authors(kana)
OrganizationThe 1st Department of Internal Medicine, Faculty of Medicine, Shinshu University, *Division of Radiology, Shinshu University Hospital
JournalThe Japanese Journal of nuclear medicine
Volume15
Number1
Page49-55
Year/Month1978/2
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] The dual radioisotope techniques with 197HgCl2 and other radionuclides were carried out using a scintillation camera coupling to a small digital computer. The tumor image was obtained using 197HgCl2, and patient remaining the same position was given 99mTc-HSA for blood pool imaging and or 99mTc-MAA for perfusion imaging. The positional pulses from the scintillation camera were fed into 4096 words memory through matrix input controller, and transferred from computer to magnetic tape recorder. Matrix images of magnetic tape were fed into the small digital computer and these images were displayed as smoothed image with 25 points weighted average on the graphic display device. The joint use of tumor imaging and blood pool imaging or perfusion imaging was useful to make isotope diagnosis of various lung diseases more reliable. The subtraction image with 197HgCl2 and 99mTc-HSA was extracted out of the original image of 197HgCl2. The location for subtraction was selected by the cursor on the image of 99mTc-HSA, and this positional information was transferred from the graphic display device to the computer in order to calculate count ratio (subtraction ratio) between two images. Count on the matrix image of 99mTc-HSA were multiplied by the subtraction ratio. This normalized image was subtracted from the tumor image. This image seemed to be valuable for detecting the lesion in the mediastinum and hilar region so that the part of non-specific concentration of 197HgCl2 on the tumor image was erased. The image as iso-count map extracted out of the image of 99mTC-MAA or 99mTc-HSA was superimoposed to the brightness image of 197HgCl2 or the subtraction image. These procedures were useful to improve anatomic orientation of the image.
PracticeClinical medicine
Keywords

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