| Japanese |
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| Title | 肺癌, 乳癌, 前立腺癌患者の99mTc-diphosphonate骨シンチグラフィの検討 |
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| Subtitle | 原著 |
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| Authors | 利波紀久*, 上野恭一*, 杉原政美*, 道岸隆敏*, 油野民雄*, 久田欣一* |
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| Organization | *金沢大学医学部核医学科 |
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| Journal | 核医学 |
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| Volume | 14 |
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| Number | 4 |
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| Page | 493-500 |
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| Year/Month | 1977/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「はじめに」99mTc標識燐酸化合物の開発と高解像力シンチカメラの登場によって骨シンチグラフィは最も有用な核医学検査法となった. 本法は悪性腫瘍の骨転移の存在診断や治療効果の判定と経過観察には不可欠であり, 悪性腫瘍患者の管理に占める役割はきわめて大きい. 骨X-Pで転移の存在が指摘される数か月以前に骨シンチグラフィで診断できることは広く認識されている. しかしながらわが国で転移性骨腫瘍における骨シンチグラフィの有用性についての報告は少ない. そこでわれわれは依頼件数の多い肺癌, 乳癌, 前立腺癌患者において骨シンチグラフィと骨X-Pの骨転移検出能の比較と転移部位別頻度についての検討を行ない, 骨転移の検索の進め方と問題点について考察したので報告する. 「対象および方法」昭和49年1月より昭和51年9月まで金沢大学核医学診療科で施行された629症例の初診の99mTc-diphosphonate骨シンチグラフィのうち, 骨X-Pとの対比が可能であった肺癌92例, 乳癌57例, 前立腺癌33例を検索対象とした. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Investigation of 99mTc-diphosphonate Scintigraphy in Patients with Lung, Breast or Prostatic Cancer |
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| Subtitle | Original Articles |
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| Authors | Norihisa TONAMI, Kyoichi UENO, Masami Sugihara, Takatoshi MICHIGISHI, Tamio ABURANO, Kinichi HISADA |
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| Authors(kana) | |
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| Organization | Department of Nuclear Medicine, School of Medicine, Kanazawa University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 14 |
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| Number | 4 |
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| Page | 493-500 |
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| Year/Month | 1977/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 99mTc-diphosphonate bone scintigrams in 92 cases of lung cancer, 57 cases of breast cancer and 33 cases of prostatic cancer were reviewed. Carcinoma of lung, breast and prostate yielded 55%, 42%, 67% bone involvement, respectively at the first performance of bone scintigraphy. Detectabilities of bone metastasis with bone scintigraphy were 92% in lung cancer, 100% in breast cancer and 95% in prostatic cancer. These results were much superior to those with bone X-P. Bone distribution from lung cancer was 65% in the rib, which was much higher than all the other sites. From breast cancer it was 67% in the rib and more than 29% in other sites except for the cervical spine and from prostatic cancer 73% in the pelvis and relatively high incidences in all of other sites. Diffuse bone involvement throughout whole skeletal system were observed in 2 cases of prostatic cancer, one case of breast cancer, and one case of lung cancer, and a typical bone scintigraphy was presented. Also one case of lung cancer showing "cold lesion" on bone scintigraphy and 3 cases of lung cancer presenting hypertrophic pulmonary osteoarthropathy were observed. Finally the diagnostic approach of bone metastasis and the appropriate process of bone scintigraphy in these malignant neoplasms were discussed. |
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| Practice | Clinical medicine |
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