| Japanese |
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| Title | 多方向像201Tl心筋スキャンによる心筋虚血の検出と部位診断 |
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| Subtitle | 原著 |
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| Authors | 分校久志*, 利波紀久*, 久田欣一* |
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| Organization | *金沢大学医学部核医学教室 |
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| Journal | 核医学 |
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| Volume | 14 |
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| Number | 4 |
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| Page | 477-484 |
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| Year/Month | 1977/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. はじめに」201Tlは一価のイオンとしてK+と同様に局所血流量に比例して血中より正常心筋細胞内に急速に取込まれることにより心筋スキャンが可能である. 201Tlはその物理的半減期が73時間と比較的長くサイクロトロンより遠隔地でも使用可能であり, またガンマカメラでの検出に適したエネルギー (167, 135keVγ線, 69〜83keVHg X線) を有しており被曝量も少ないなど心筋スキャン用剤として理想的な核種といえる. 著者らは先に201Tl心筋スキャンの基礎的検討として201Tl投与後早期の体外計測による臓器集積の検討を行ない, 梗塞部対正常部心筋集積比が平均0.74 (静注10分後) と比較的高いことを報告した. 今回著者らは多方向撮像による安静時201Tl心筋スキャンでの心筋虚血部の検出と部位診断について検討したので報告する. 「II. 対象および方法」今回の検討は虚血性心疾患を有するかまたは有すると考えられた症例39例, 先天性心疾患および心臓手術後患者7例, 正常例有志2例, 計48例53回の201Tl心筋スキャンについて行なった. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Detection and Localization of Myocardial Ischemia with Multiple View 201Tl Myocardial Imaging |
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| Subtitle | Original Articles |
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| Authors | Hisashi BUNKO, Norihisa TOMANI, Kinichi HISADA |
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| Authors(kana) | |
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| Organization | Department of Nuclear Medicine, School of Medicine, Kanazawa University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 14 |
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| Number | 4 |
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| Page | 477-484 |
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| Year/Month | 1977/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 201TI accumulates rapidly into myocardial cell and its distribution depends on viability and degree of perfusion. We intended to evaluate detectability and localization of myocardial ischemia on multiple view 201Tl myocardial imaging. Multiple view imaging of myocardium was started from 5 minutes after 1-2mCi of 201Tl I.V. injection and included anterior, 30°LAO, 60°LAO, left lateral and 30°RAO views. It took 4-6 minutes for imaging single view and whole study was completed within 40-50 minutes using high resolution collimator and Hg X-ray of 201Tl. Fifty-three cases were included in this study (17 cases with old myocardial infarction (MI) , 9 cases with angina and those suspected of having MI, 16 cases with ischemic heart disease other than above mentioned, 6 cases with congenital heart disease, 3 cases with cardiac surgery and 2 normal volunteers) . All of 6 cases who showed marked focal defect had MI. Of the 12 cases who showed focal defect, 8 cases had MI and 2 cases had cardiac surgery. Three cases with MI (anterolateral, lateral subendcardial and inferior infarction) were equivocal and thought to be false negatives. Detectability of old MI was 82% and in 86% of these cases localization of abnormality agreed with ECGs. Of these cases 3 showed larger and 1 showed smaller abnormal area than ECGs. Five cases without MI or cardiac surgery showed decreased activity at apex. Rest ECGs of these cases were all within normal limits. However, decreased activity at apex on 30°and/or 60°LAO views was thought to be abnormal. Twelve cases showed right ventricular wall accumulation and 10 of these cases had congestive heart failure. From these results we concluded that multiple view 201Tl myocardial imaging was acculate and useful for detection and localization of myocardial ischemia, and that right ventricular wall visualization was good index for right hesrt strain. |
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| Practice | Clinical medicine |
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