| Japanese |
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| Title | 99mTc-(Sn)DTPAによるラジオアイソトープ腎アンギオグラフィー - 腎嚢腫疾患と腎実質腫瘍の鑑別について - |
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| Subtitle | 原著 |
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| Authors | 大石幸彦*,**, 飯尾正宏*, 千葉一夫*, 山田英夫*, 松井謙吾*, 村田啓*, 町田豊平**, 三木誠**, 工藤潔**, 谷野誠** |
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| Authors(kana) | |
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| Organization | *東京都養育院付属病院核医学放射線部, **東京慈恵会医科大学泌尿器科 |
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| Journal | 核医学 |
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| Volume | 14 |
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| Number | 4 |
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| Page | 461-476 |
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| Year/Month | 1977/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「緒言」203Hg-neohydrinおよびその他多くの腎スキャン剤による腎シンチグラフィーでは, 機能相functional phaseの静的イメージから判断する限り, 腎病変は放射能の低下ないし欠損部として表わされる. すなわち, 腎嚢腫, 多発性嚢胞腎, 腎癌, 腎血管腫, 腎結核, 腎梗塞などのspace occupying lesion (以下SOLと略す) は, すべて通常の腎スキャン剤によるイメージでcold lesionとして表わされ, その病変部の質的診断は不可能である. 近年, 静脈注射で腎の血流分布状態を知る方法としてradioisotope (以下RIと略す) 腎アンギオグラフィーが登場し, SOLの鑑別診断に応用されてきている. RI腎アンギオグラフィー用の試薬としてGFR物質99mTc-(Sn)DTPAは腎からの排泄が早く, 腎動態機能検査に適した物質であるといわれている. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Radioisotope Renal Angiography by 99mTc-(Sn)DTPA - On the Differentiation of Renal Cystic Diseases and Renal Parenchymal Tumors - |
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| Subtitle | Original Articles |
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| Authors | Yukihiko OHISHI*,**, Masahiro IIO*, Kazuo CHIBA*, Hideo YAMADA*, Kengo MATSUI*, Hajime MURATA*, Toyohei MACHIDA**, Makoto MIKI**, Kiyoshi KUDOH**, Makoto TANINO** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine and Radiological Science, Tokyo Metropolitan Geriatric Hospital, **Department of Urology, The Jikei University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 14 |
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| Number | 4 |
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| Page | 461-476 |
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| Year/Month | 1977/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Radioisotope renal angiography was performed using 99mTc-(Sn)DTPA to evaluate the value of the differential diagnosis between renal cystic diseases and renal parenchymal tumors. Differential diagnosis is based on the perfusion image in the vascular phase obtained by intravenous injection of 99mTc-(Sn)DTPA. The subjects were 32 cases with renal space occupying lesions consisting of 17 renal cysts, 2 polycystic kidneys, 12 renal carcinomas and 1 renal hemangioma. Patients were consisted from 20 males and 12 females ranging from 11 to 80 y.o. (mean 60.2y.o.). Searle Pho/Gamma IV with data store playback system and diverging collimator was used. Ten mCi of 99mTc-(Sn)DTPA was rapidly injected intravenously as a bolus. Seqential vascular phase images were obtained at every 5 seconds interval for 10 to 40 seconds. Functional phase images were then obtained every 1 to 3 minutes for 20 minutes after injection. Later gamma camera renogram were obtained by setting adequate regions of interest (ROI) for right and left kidneys. Vascular phase images of 99mTc-(Sn)DTPA were compared with final diagnosis by operation, autopsy, renal angiogram and nephrotomogram. In all cases, renal scintigram were obtained by intravenous injection of 300μCi of 203Hg-neohydrin and the scintigrams were compared with functional phase images of 99mTc-(Sn)DTPA. In functional phase images of 99mTc-(Sn)DTPA or 203Hg-neohydrin scintigram, all lesions were revealed as areas of cold region. However, in the vascular images obtained by 99mTc-(Sn)DTPA, lesions of 12 renal carcionmas and 1 renal hemangioma appeared as hot areas, showing the presence of fluent arterial perfusion. One renal carcinoma, 17 renal cysts and 2 polycystic kidneys were depicted as cold areas, representing the absence of arterial perfusion. In conclusion, radioisotope renal angiography by 99mTc-(Sn)DTPA were found to be usefull aid for differential diagnosis of the nature of space occupying lesions of the kidney. This technique is applicable safely on such cases as with poor risk, with aged or with iodosyncrasy to the iodine contrast dyes. |
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| Practice | Clinical medicine |
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