| Japanese |
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| Title | 脊髄小脳変性症におけるCisternographyについて - 111In-DTPA使用による検討 - |
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| Subtitle | 原著 |
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| Authors | 藤田真佐之*, 宮崎元滋*, 金尾啓右**, 本田稔**, 石原静盛** |
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| Organization | *住友病院神経内科, **RI室 |
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| Journal | 核医学 |
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| Volume | 14 |
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| Number | 4 |
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| Page | 451-460 |
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| Year/Month | 1977/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「はじめに」脳脊髄液 (CSF) の動態および脳槽, 脳室の形態判定において, RI-Cisternographyは不可欠のものとなってきた. 特に近年169Yb-DTPAの出現から, さらにより理想的核種である111In-DTPAの出現により, 患者に対する侵襲および危険性はほとんど恐れる必要がない状態となっている. 対象疾患は, Di Chiroの発表以来, CSF rhinoand otorrhea, hydrocephalus, tumor (intraventricular and intraspinal) , Cyst, neurosurgical shuntの流通判定, さらにCSF dynamicsの測定等多岐にわたっている. また, normal pressure hydrocephalus (以下NPHと略す) の存在とそのshunt手術による改善についての知見が増加するにつれて, NPHを疑わせる症状を有する患者に広く検討されるようになり, CSF動態の正常限界, Dementiaにおけるpattern, 高齢者のCSF循環の変化などの知見が明らかにされてきた. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Cisternographic Finding in Spinocerebellar Degeneration with 111In-DTPA |
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| Subtitle | Original Articles |
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| Authors | Masashi FUJITA*, Motoji MIYAZAKI*, Keisuke KANAO**, Minoru HONDA**, Shizumori ISHIHARA** |
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| Authors(kana) | |
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| Organization | *Sumitomo Hospital Department of Neurology, **Division of Nuclear Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 14 |
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| Number | 4 |
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| Page | 451-460 |
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| Year/Month | 1977/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Radio-cisternogtaphic studies were performed using 111In-DTPA in fifteen patients diagnosed as spinocerebellar degeneration and their resutls were compared with those obtained in the control group. In the spinocerebellar degeneration group, about 80% of the patients showed filling and retention of 111IN-DTPA in the posterior fossa in contrast to about 17% in the control group at 6 and 24 hours after intrathecal injection of rediopharmaceuticals. In some cases, filling of lateral ventriculus, delayed circuration and partial subarachnoid block of the radiopharmaceuticals were noted. However these cases were equally present on both groups. These results seem to demonstrate the accumulation of the isotope in the enlarged posterior fossa caused by the atrophied cerebellum. This method may be helpfull as one of the diagnostic procedures to prove cerebellar atrophy. 111In-DTPA clearance was also studied. No adverse reaction was noted. |
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| Practice | Clinical medicine |
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| Keywords | |
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