| Japanese |
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| Title | 123Iによる甲状腺機能検査 |
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| Subtitle | 原著 |
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| Authors | 三枝健二*, 有水昇*, 内山暁*, 川名正直*, 国安芳夫*, 多田式江* |
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| Organization | *千葉大学医学部放射線医学教室 |
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| Journal | 核医学 |
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| Volume | 14 |
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| Number | 4 |
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| Page | 443-449 |
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| Year/Month | 1977/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. はじめに」甲状腺検査のうち, in vivoで行なわれる甲状腺摂取率測定およびシンチグラフィには, これまで131Iが広く利用されてきたが, 最近, これに代わる短半減期核種123Iがサイクロトロンで生産され始め, わが国でもこれがルーチンに使用できるようになった. 123Iは半減期13.3時間, 主ガンマ線エネルギー159keV (83%) で, その特徴は131Iに比べて患者への被曝線量が少なく, かつ短半減期の繰返し検査が可能な点にある. 現在のところ, 価格が高いという欠点はあるが, われわれの教室では昭和51年3月より131Iカプセル (50μCi) の患者への投与を, 全面的に123Iカプセル (日本メジフィジックス社製100μCi) に切替え使用している. 123Iと131Iの基礎的, 臨床的比較はすでに報告してあるが, 今回は123I投与後の検査時期について検討を加えたのでここに報告する. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Thyroid Studies with Iodine-123 |
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| Subtitle | Original Articles |
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| Authors | Kenji SAEGUSA, Noboru ARIMIZU, Guio UCHIYAMA, Masanao KAWANA, Yoshio KUNIYASU, Norie TADA |
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| Authors(kana) | |
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| Organization | Department of Radiology, Faculty of Medicine, Chiba University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 14 |
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| Number | 4 |
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| Page | 443-449 |
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| Year/Month | 1977/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Iodine-131 has been routinely used for thyroid studies as the standard agent since 1955 in Japan Recently, the cyclotron-produced iodine-123 has been supplied for clinical uses in Japan by Nihon Medi-Physics Incorporation. The physical features of iodine-123 make it the closest to the ideal for thyroid scintigraphy of any nuclides, because of its relative-short half-life of 13.3 hours and its major gamma-ray peak of 159keV. The main advantages of iodine-123 are low exposures to the thyroid of patient, roughly calculated as low as approximately one hundredth of iodine-131. The purpose of this study is to evaluate the resonable time for the thyroid studies with iodine-123, especially in scintigraphy, in case of oral administration. The clinical studies were performed on a variety of thyroid functions of 277 cases. The results showed that thyroid scintigrams obtained at 3 to 6 hours were better in image quality than those of 24 hours in ninety percent of the cases, because of increases in information densities. In the rest of ten percent, the image quality was almost same in the both scintigraphic times. Otherwise, the thyroid uptake measurements were possible at 3 and 24 hours after oral administration. In a majority of cases studied, the measurements at 3 hours still offered useful informations regarding thyroid functions, being substitutive for those of 24 hours. It is properly suggested that the thyroid scintigraphy and uptake measurements with iodine-123 had better be taken in routine studies at 3 hours after oral administration. |
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| Practice | Clinical medicine |
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| Keywords | |
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