Japanese
Title脳室短絡系路内の脊髄液流量測定法 - ファントーム実験 -
Subtitle研究速報
Authors前田敏男*, 森厚文*, 久田欣一*,***, 角家暁**,****
Authors(kana)
Organization*金沢大学医学部核医学科, **金沢医科大学脳神経外科, ***主任教授, ****主任
Journal核医学
Volume14
Number2
Page297-301
Year/Month1977/4
Article報告
Publisher日本核医学会
Abstract「はじめに」水頭症の治療に脳室腹腔短絡術や脳室心房短絡術が行なわれている. 最近リザーバ内に注入したRIのクリアランスから短絡系路内の脳脊髄液流量を測定できるようになった. 「方法」Standard Rickham reservoirにHolter systemを組合わせた装置 (Rickham-Holter装置と略す) と直径12mmのPudenz装置について実験を行なった. 各々の装置をPiker Dyna Camera 2.cの直下でサイフォンの原理を応用して作動させた. Harbertらの報告値と比較するためにHarvard infusion pumpで流量を決定した実験も行なった. リザーバに1〜2mCi/mlの90mTc pertechnetate (99mTCO4- と略す) を26Gの注射針を付けたツベルクリン用注射器で0.05ml注入した. 注入直後より関心領域をリザーバ部に設定し10秒毎 (流量が0.5ml/分以上の時は4秒毎) のリザーバ部のtime activity curve (クリアランス曲線) を約10分間記録した.
Practice臨床医学:一般
Keywords
English
TitleExamination of Cerebrospinal Fluid (CSF) Flow Rate Through the Implanted Shunts - Phantom Experiments -
Subtitle
AuthorsToshio MAEDA*, Hirofumi MORI*, Kinichi HISADA*, Satoru KADOYA**
Authors(kana)
Organization*Dept. of Nuclear Medicine, Kanazawa Univ. Medical School, **Dept. of Neurosurgery, Kanazawa Medical College
JournalThe Japanese Journal of nuclear medicine
Volume14
Number2
Page297-301
Year/Month1977/4
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] We performed phantom examination to determine CSF flow rate through the ventricular shunt, (Rickham-Holter system and Pudenz system) . The shunt systems operated as siphon under the gamma camera. 99mTcO4- of 50 to 100μCi was injected into the reservoir and removal of it from the reservoir was expressed as a time-activity curve, and clearance half-time (T1/2) of radioactivity was determined from this curve. Increased weight in lower container divided by the duration of the water transfer yielded the flow rate (F) . T1/2 and F were plotted on double-log scale and they showed linear relationship. In Rickham-Holter system, the regression equation was log10(F)=-1.91 log10(T1/2)-0.032 and in Pudenz system it was log10(F)=-1.03 log10(T1/2)-0.02. The data of Pudenz system were as the same as that of Harbert's report. In the case of Rickham-Holter system, however, our results showed that experimental volume (Vexp) changed with flow rate (Table 1) , while Harbert et al. reported that Vexp was constant. Then we re-examined according to Harbert's method using Harvard infusion pump and confirmed that our data were proper. Therefore, the above regression equation for each reservoir should be used to calculate CSF flow through the shunt.
PracticeClinical medicine
Keywords

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