| Japanese |
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| Title | 99mTc EHDPと全身カメラによる転移性骨腫瘍の骨スキャニング |
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| Subtitle | 原著 |
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| Authors | 中野俊一*, 長谷川義尚*, 小松原良雄*, 梶田明義*, 石上重行** |
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| Organization | *大阪府立成人病センター, **大阪大学微生物病研究所附属病院内科 |
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| Journal | 核医学 |
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| Volume | 14 |
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| Number | 2 |
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| Page | 233-241 |
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| Year/Month | 1977/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. はじめに」骨スキャンは85Sr, 87mSr, 18Fなどを使用して行われてきたが, 現在では1971年Subramanianらにより報告された99mTcポリ燐酸及びこれに続いて開発されたピロ燐酸, diphosphonateなど一連の99mTc標識燐酸化合物が, 半減期, 骨への集積程度などの点よりすぐれた薬剤として用いられている. われわれは昭和50年より99mTc EHDP (ethanel-hydroxy-1, 1-diphosphonate) と全身カメラ装置を用いて転移性骨腫瘍の診断を行ない, 特に骨に転移し易い肺癌, 乳癌などにおいては病期の決定, 治療法の選択などに極めて重要な指針を与え, 不可欠の検査であることを確かめた. 本稿においては現在までに得た成績を中心に骨スキャン像の判読上の問題点を述べたい. 「II. 検査対象並びに方法」「1. 検査対象」最近1年間に大阪府立成人病センターRI科を受診した種々の癌症例のうち70例について76回の検査を行なった. 症例の内訳は肺癌44例, 乳癌9例, 子宮癌4例, 腎癌3例, 胃癌3例, その他7例である. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Bone Scanning by Whole Dody Camera with Tc-99m Diphosphonate |
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| Subtitle | Original Articles |
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| Authors | Shunichi NAKANO*, Yoshihisa HASEGAWA*, Yoshio KOMATSUBARA*, Akiyoshi KAJITA, Shigeyuki ISHIGAMI** |
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| Authors(kana) | |
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| Organization | *The Center for Adult Diseases, Osaka, **The Research Institute for Microbial Diseases, Osaka University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 14 |
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| Number | 2 |
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| Page | 233-241 |
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| Year/Month | 1977/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Clinical usefulness of the whole body scintigrams for detection of metastatic bone tumors was studied with Tc-99m-diphosphonate (Nihon Mediphysics) and moving table whole body imaging system (Toshiba 202) on 70 patients with malignant lesions. The scans were performed 4-6 hours after the injection, based on the curve of blood disappearance and spine-to-background ratio. All cases were examined not only by scanning the whole body with the moving mode but also by scanning the trunk with the stationary mode and then both images were compared. All foci of the abnormal accumulation, even small ones of ribs and bones of hand and foot, detected with the stationary mode could be identified on the moving images as well. So the whole body imaging system was proved to be as sensitive as stationary camera and found to save time necessary for examination. Upon evaluating the image of bone scanning, the undesirable accumulation in colon must not be mistaken for the abnormal accumulation in the pelvis, because 27 out of 70 cases examined showed undesirable images of coecum and/or ascending colon 4 hours after injection of Tc-99m-diphosphonate. There were a few reports that the metastatic bone lesions did not always accumulate more radioactivity than normal counterpart. A similar case was experienced by us in lung cancer. In 35 out of these 70 cases (50%) abnormal accumulation of radioactivities were found. The details were as follows ; pulmonary cancer 19/44, mammary cancer 7/9, uterine cancer 2/4, renal cancer 2/3, gastric cancer 2/3, and others 3/7. These positive rates were higher than those reported based on radiographic or necroptic bone survey, suggesting that the bone scanning is more sensitive in detection of metastatic bone tumors than the conventional bone survey. In conclusion, bone scanning with Tc-99m-diphosphonate and whole body camera is found to be very useful in detection of metastatic bone tumors. |
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| Practice | Clinical medicine |
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