Japanese
Title鑑別診断におけるHead scan (99mTc - EHDP Brain scan) の臨床的意義
Subtitle原著
Authors小林真*, 前田敏男*, 森厚文*, 利波紀久*, 久田欣一*, 松平正道**
Authors(kana)
Organization*金沢大学医学部核医学科, **金沢大学病院中央アイソトープ部
Journal核医学
Volume14
Number1
Page51-57
Year/Month1977/2
Article原著
Publisher日本核医学会
Abstract「I. 緒言」骨スキャン用放射性医薬品として, 1971年Subramanianらにより開発された99mTc標識リン酸化合物の進歩は著しいものがあるが, 最近以上の99mTc標識リン酸化合物が脳梗塞をはじめとする骨組織以外の病巣に集積したとの報告がなされているが, 我々は99mTc-EHDPによる脳スキャン(以下Head scan)を従来の99mTc-pertechnetateによる脳スキャン(以下Brain scan)と併行して施行し両者のスキャン所見より脳梗塞と脳腫瘍の鑑別が可能か否か検討した. 「II. 対象および方法」対象は手術, 脳血管撮影, もしくは臨床経過より確定診断のついた症例41例で, 全スキャン施行回数48回を対象とした. 脳梗塞は再スキャンを含めて33例, 脳腫瘍15例であった. 脳腫瘍の内訳はTable 1に示した様に転移性脳腫瘍6例, 髄膜腫5例, 星細胞腫, 乏突起膠芽腫, 聴神経鞘腫が各1例, 1例は未手術例で組織型は不明であった.
Practice臨床医学:一般
Keywords
English
TitleClinical Utility of Head Scan - 99mTc - EHDP Brain Scan - in Differentiating Cerebral Infarction from Cerebral tumors
SubtitleOriginal Articles
AuthorsShin KOBAYASHI*, Toshio MAEDA*, Hirofumi MORI*, Norihisa TONAMI*, Kinichi HISADA*, Masamichi MATSUDAIRA**
Authors(kana)
Organization*Department of Nuclear Medicine, School of Medicine, Kanazawa University, **The Central Clinical Isotope Division, Kanazawa University Hospital
JournalThe Japanese Journal of nuclear medicine
Volume14
Number1
Page51-57
Year/Month1977/2
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractA study utilizing both 99mTc-pertechnetate and 99mTc-diphosphonate was under-taken to evaluate the recent observation that some cerebral infarctions are better defined with 99mTc-labeled phosphate complex than with 99mTc-pertechnetate and that the reverse pattern may occur in cerebral tumors. Each of 41 patients was studied with two separate brain scans performed sequentially after the injection of 10-15mCi of 99mTc-pertechnetate or 10-15mCi of 99mTc-diphosphonate. Each of 99mTc-pertechnetate brain scan(brain scan)and 99mTc-diphosphonate brain scan(head scan)was performed separately 48 times including re-examination. The resulting scans were qualitatively compared, and target-to-nontarget ratios of intensity determined. Diagnoses were established by surgery in 10, by cerebral roentgen angiography in 3 and by clinical course in 2 of 15 cases of cerebral tumors. In eight of 33 cases of cerebral infarction, the clinical diagnoses were supported by cerebral roentgen angiography. The target-to-nontarget ratio in cerebral infarction was greater with 99mTc-diphosphonate than with 99mTc-pertechnetate in 19 Cases, equal in 6 Cases. Remaining 8 cases were not detected with both scan. In contrast to cerebral infarction, the target-to-nontarget ratio was greater with 99mTc-pertechnetate than with 99mTc-diphosphonate in 10 cases, equal in 3 cases, and less in 2 cases of cerebral tumors. In conclusion, these results indicate that this dual method is helpful in differentiating cerebral tumors from cerebral infarction. And correlation of abnormal brain scans with skull film is essential.
PracticeClinical medicine
Keywords

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