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| Title | Improvement of Findings on Bone Image in Prostatic Cancer Following Testosterone Potentiated 32P Therapy |
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| Authors | Kazuo ITOH*, Norihisa TONAMI*, Shin KOBAYASHI*, Yutaka SUZUKI*, Kinichi HISADA* |
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| Organization | *From the Department of Nuclear Medicine School of Medicine Kanazawa University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 13 |
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| Number | 6 |
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| Page | 825-829 |
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| Year/Month | 1976/12 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Abstract] Improvement of metastatic bone lesions on 99mTc-diphosphonate bone scanning is demonstrated in a patient of prostatic cancer following the treatment of testosterone potentiated radiophosphorus. [Index terms]: Prostate, prostatic cancer, metastatic Bone, bone scan, metastatic, Agents, radiophosphorus, testosterone, 99mTc-diphosphonate. Since Subramanian and McAfee (1.2) prepared technetium-99m polyphosphate complexes for bone imaging in nuclear medicine, many disease entities causing an increased uptake of bone seeking radiopharmaceuticals have been reported (3, 4, 5, 6). Skeletal metastatic foci in the prostatic carcinoma are sure to be abnormally accumulated by the bone seeking radiopharmaceuticals (7, 8). However, evaluation of destruction and regeneration of the involved metastiatic bone lesions after 32P therapy with or without testosterone priming has been carried out mostly by the X-ray examination (9, 10, 11, 12). |
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| Practice | Clinical medicine |
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| Japanese |
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| Title | 男性ホルモン併用32P治療に骨イメージの改善を認めた前立腺癌多発性骨転移の一症例 |
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| Subtitle | 臨床報告 |
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| Authors | 伊藤和夫*, 利波紀久*, 小林真*, 鈴木豊**, 久田欣一*,*** |
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| Organization | *金沢大学医学部核医学講座, **現在東海大学医学部放射線科, ***主任教授 |
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| Journal | 核医学 |
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| Volume | 13 |
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| Number | 6 |
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| Page | 825-829 |
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| Year/Month | 1976/12 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要約」多発性骨転移の為に耐えがたい治療抵抗性骨疼痛を有する前立腺癌患者に対し, 疼痛緩和及び骨転移巣の改善を目的として男性ホルモン(テストステロン)導入による32P治療を施行した. 使用後, 約3〜4日目に劇的な骨疼痛の改善を認め, さらに約1ヶ月後の骨イメージにも改善が認められた. これまで, 骨スキャンが骨転移の早期発見に非常に有効であるとされているが, 本症例の如く骨転移病巣の治療効果の判定にも役に立つ可能性が考えられ, 興味ある症例と思われたので報告した. 尚, 32P治療によると思われる重篤な副作用は認めなかった. |
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| Practice | 臨床医学：一般 |
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