Japanese |
Title | Bone Mineral Analyzerによる骨塩定量 |
Subtitle | 原著 |
Authors | 山本逸雄*, 土光茂治*, 福永仁夫*, 鳥塚莞爾*, 高坂唯子**, 森田陸司**, 浜本研*** |
Authors(kana) | |
Organization | *京都大学医学部放射線科, **中央放射線部, ***愛媛大学医学部放射線科 |
Journal | 核医学 |
Volume | 13 |
Number | 6 |
Page | 759-767 |
Year/Month | 1976/12 |
Article | 原著 |
Publisher | 日本核医学会 |
Abstract | 「I. はじめに」骨塩定量は, 骨粗鬆症や骨軟化症等の骨塩減少をきたす疾患の診断や, 経過観察において重要な問題であるが, 日常の診療において行われているX線写真の読影による方法では, 骨塩量の25%以下の変動はとらえがたく, 定量はできない. 一方, X線写真より骨塩を定量化しようとする試みは古くからあり, 低エネルギーX線を用い, 厳密な一定の条件のもとで撮影, 現像し, そのフィルム濃度の変化を光学機械を用いて定量化し, アルミニウムやハイドロキシアパタイト等の濃度との比較においてあらわす方法は, 数々の改良により, 数%以内の誤差といわれるまでに進歩したが, その手技は煩雑であり, 以下に述べるphoton-absorptiometryにくらべて再現性は劣ると言われている. |
Practice | 臨床医学:一般 |
Keywords | |
English |
Title | Bone Mineral Content Measurement by Bone Mineral Analyzer |
Subtitle | Original Articles |
Authors | Itsuo YAMAMOTO*, Shigeharu DOKOH*, Masao FUKUNAGA*, Kanji TORIZUKA*, Tadako KOSAKA**, Rikushi MORITA**, Ken HAMAMOTO*** |
Authors(kana) | |
Organization | *Department of radiology, Kyoto university Hospital, **Central division of radiology and radioisotopes, Kyoto university hospital, ***Department of radiology, Ehime university hospital |
Journal | The Japanese Journal of nuclear medicine |
Volume | 13 |
Number | 6 |
Page | 759-767 |
Year/Month | 1976/12 |
Article | Original article |
Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
Abstract | [Summary] With the bone mineral analyzer (Studsvik Bone Scanner 7102), bone mineral content (BMC) was validated using standard material of CaCO3 with various concentrations primarily. Seventy-five normal subjects, nineteen patients with rheumathoid arthritis (RA) and twenty-two patients with abnormal thyroid function were investigated by this method. Some inherent problems concerning the present measurements were also discussed. Reproducibility of BMC measurements in sixteen normal subjects between four months interval was +- 4% in S.D. value on the mid-shaft of the radius and +- 5% on the distal head of the radius, respectively. Although correlation of the single energy method and the dual energy method with the bone scanner was high (r=0.970), the single energy method was liable to be underestimated probably due to fat layer. BMC in normal subjects was highest in 30 and 40 decades for both males and females, and gradually decreased with aging. Males had higher BMC and BMC/bone width than females. All of stage 1 group of RA patients, according to roentgenographic staging, revealed normal BMC, but most of stage 2 and 3 groups abnormally low BMC, suggesting that the progression of the disease may be an important factor on BMC values. BMC of hyperthyroid patients revealed lower value, whereas euthyroid patients revealed normal value. Serial measurements of BMC in a hyperparathyroid patient and a hyperthyroid patient revealed distinct recurrence of BMC after treatments. |
Practice | Clinical medicine |
Keywords | |