| Japanese |
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| Title | 加齢による慢性日本住血吸虫症の肝サイズ及び形態変化についての検討 (肝シンチグラムによる追跡検査) |
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| Subtitle | 原著 |
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| Authors | 井内正彦*, 湯村和子*, 前田淳*, 相沢孝夫*, 木谷健一** |
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| Organization | *甲府市立病院内科, **東京都老人総合研究所生理研究部臨床第一研究室 |
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| Journal | 核医学 |
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| Volume | 13 |
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| Number | 2 |
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| Page | 123-127 |
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| Year/Month | 1976/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「1. 緒言」加齢による臓器の形態的, 機能的変化を追求する場合, その研究方法としてはcross sectionalな観察が主体をなし, 特に人のようにlife spanの長い対象を扱う場合は, これをlogitudinalに観察することは多くの困難が伴なう. また, 肝臓のような臓器の形態の変化を扱う場合, その方法論からいっても剖検によるcross sectional studyがあるのみである. しかし, 高齢者群が, 若齢者群のrandom survivorである保証はなく, その研究の前提が誤りであることも多い. 従って, 種々のcross secti onal studyの他に, 数少ない機会をとらえて, 同じパラメータをlongitudinalに追求し, 両者を比較することが望まれる. 著者らは山梨県甲府盆地に残存する, 慢性日本住血吸虫症患者についての長期間の追跡調査を行なっているが, その手段の一つとして, 過去7年間余り, 肝シンチグラムによる肝の形態変化, 容積の変化について検討してきた. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Changes in the Liver Size and Shape in Patients with Chronic Mild Schistosomiasis Japonica Studied by Liver Scintigram. |
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| Subtitle | Original Articles |
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| Authors | M IUCHI, K YUMURA, A MAEDA, T AIZAWA, K KITANI* |
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| Organization | Department of Medicine, Kofu city hospital, *First Laboratory of Clinical Physiology, Tokyo Metropolitan Institute of Gerontology |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 13 |
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| Number | 2 |
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| Page | 123-127 |
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| Year/Month | 1976/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The relation between the changes in the liver size and shape and age of patients with chronic schistosomiasis japonica was studied with the use of liver scintigram using 198Au colloid 1) Longitudinal study for the changes in liver size. One hundred and twenty nine patients with positive skin test for schistosomiasis and mild liver damage (histologically normal range to only liver fibrosis) were studied longitudinally for five years in order to know the changes in liver size in relation to the age of patients. The frontal plane of the liver measured planimetrically was used as an index of liver size. The incidence of more than 10% decrease of frontal plane area in 5 years was 37.5% (12/32 cases) in patients with the age more than 70, while no O such case was observed in patients under the age of 60. 2) Cross sectional study for the elavation of the right dome of the liver. The incidence of the elevation of the right dome of the liver observed in the liver scintigram was examined in 734 control patients without liver diseases and with negative skin test and in 1555 patients with chronic schistosomiasis. The incidence of the right dome elevation was high in patients over 70 years of age in both groups of patients, particularly in female patients. However, the incidence was significantly higher in control group. |
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| Practice | Clinical medicine |
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