| Japanese |
|---|
| Title | 排泄尿中57Co-Bleomycinの処理に関する研究 |
|---|
| Subtitle | 原著 |
|---|
| Authors | 鳥住和民*, 三島隆生*, 前田真行*, 根来良典*, 岡本牧子*, 藤野保定*, 堀啓二*, 桜井武雄** |
|---|
| Authors(kana) | |
|---|
| Organization | *和歌山県立医科大学付属病院 放射線科, **胸部外科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 13 |
|---|
| Number | 1 |
|---|
| Page | 1-6 |
|---|
| Year/Month | 1976/2 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「緒言」最近, 悪性腫瘍にR.I.を選択的に取り込ませて陽性像として描画するtumor scanningが注目されている. 1963年Dewey等による131I-antifibrin antibodyを始めとして, 以後数多くの研究者により腫瘍親和性R.I.の開発, 臨床的応用が探求されてきた. 1972年Renault, et al. 前田等により開発された57Co-Bleomycin(以下57Co-BLMと略)はβ線を放出せず, γ線エネルギーは122KeV, 135KeVと検出上都合が良く, 血中より消失速度が大であるため早期に高い腫瘍対血液比を示し, 67Ga-citrate, 169Yb-citrateのような骨, 肝臓への集積がほとんどなく, 頭頸部, 肺部, 腹部の悪性腫瘍診断上できわめて優れたR.I.であると報告され, また三島, 等もその有用性について報告した. しかしながら57Coの物理的半減期は270日と非常に長い. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | |
|---|
| English |
|---|
| Title | Removal of 57Co-Bleomycin from urine |
|---|
| Subtitle | Original Articles |
|---|
| Authors | Kazutami TORIZUMI, Takao MISHIMA, Masayuki MAEDA, Ryosuke NEGORO, Makiko OKAMOTO, Yasusada FUJINO, Keiji HORI, Takeo SAKURAI* |
|---|
| Authors(kana) | |
|---|
| Organization | Department of Radiology, Wakayama Medical College, *Department of Thoracic Surgery, Wakayama Medical College. |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 13 |
|---|
| Number | 1 |
|---|
| Page | 1-6 |
|---|
| Year/Month | 1976/2 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] The head, neck and lung scans with 57Co-Bleomycin are very useful for the diagnosis of malignant tumors. 57Co-Bleomycin is one of good tumor scanning agents, but its 270days physical half life might be too long. 57Co-Bleomycin is rapidly eliminated through kidneys after injection ; about 90% of radioactivity is found in urine in the first 24 hours. Therefore, environmental contamination by 57Co-Bleomycin is a great problem. So, we studied the methods of the removal of 57Co-Bleomycin from urine. In this paper the results by the following four methods are described. [1) Boiling Method] The urine is boiled with the filter paper. Water is escaped in vapor, and as a result 57Co-Bleomycin is adsorbed in the filter paper. 57Co-Bleomycin is not volatilized. The removal efficiency of filter paper was more than 96% under different conditions of urines. [2) Charcoal Method] (Removal of 57Co-Bleomycin, from urines by "SIRASAGI-A" charcoal) a. Centrifuging Method b. Column Method c. Precipitation Method The removal efficiency from 1500ml of urine by each of the three methods was about 95% with 4〜5g of charcoal at 18℃, that is, there was no difference. In order to use the charcoals with good performance, it was necessary to be removed within two days. Nowadays we collect and stock the urine during the first 24hours. And we adopt the "Precipitation Method" as to urines within two days, the "Boiling Method" as to urines more than three days. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | |
|---|