| Japanese |
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| Title | 99mTc-Sn-colloidによる肝シンチグラフィー (II) 診断的意義と臨床応用 (198Au-colloidとの比較) |
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| Subtitle | 原著 |
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| Authors | 木村和文*, 西村恒彦**, 武田裕**, 古川俊之**, 梶谷文彦*** |
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| Organization | *大阪大学医学部付属病院中央放射線部, **大阪大学医学部第一内科, ***大阪大学工学部電子工学科 |
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| Journal | 核医学 |
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| Volume | 12 |
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| Number | 4 |
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| Page | 349-358 |
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| Year/Month | 1975/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「1. 緒言」放射性同位元素による肝シンチグラフィーは非観血的検査法として, 肝の大きさ, 位置の異常および局在性疾患の診断に極めて有効である. 従来より用いられている198Au-colloidによる肝シンチグラフィーの診断的意義については広く検討されている. すなわち, 肝癌などにおける欠損像のみならず, び漫性疾患についても肝硬変症における脾影の出現状況などが肝シンチグラム読影上の有効な診断情報とされている. 一方, 放射性コロイドによる肝循環動態についてはDobsonらによるCrPO4コロイドの報告をはじめVetter, 上田らにより198Au-colloidを肝血流量測定に応用する方法が実用化され肝疾患の病態の把握に有用な検査法となっている. そこで第I編において基礎的検討を行った電解法による99mTc-Sn-colloidを用いて, 各種肝疾患症例において, 肝シンチグラフィーおよびRI動態曲線を求め, 本コロイドの形態的および機能的肝RI検査法としての診断的意義を検討した. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Evaluation of the Liver Scintigraphy with 99mTc-Sn-colloid II. Clinical Studies by Comparison with 198Au-colloid |
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| Subtitle | Original Articles |
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| Authors | Kazufumi KIMURA*, Tsunehiko NISHIMURA**, Hiroshi TAKEDA**, Toshiyuki FURUKAWA**, Fumihiko KAJIYA*** |
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| Authors(kana) | |
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| Organization | *Department of Radiology and Nuclear Medicine. Osaka University Medical School, **The First Department of Internal Medicine, Osaka University Medical School, ***Department of Electric Engineering, Faculty of Engineerring, Osaka University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 12 |
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| Number | 4 |
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| Page | 349-358 |
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| Year/Month | 1975/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Clinical significance of the liver scintigraphy with 99mTc-Sn-colloid was evaluated in comparing with those with 198Au-colloid. The liver scintigrams with 99mTc-Sn-colloid and 198Au-colloid were done in 36 cases of various hepatic diseases and RI accumulation curves in the liver and the spleen, and the blood disapearance curves were also obtained. The conclusions were as follows. 1. The liver scintigrams with 99mTc-Sn-colloid proved to be more sensitive in the detection of tumors, especially, in the lower margin, left lobe and superficial layers of the liver than those with 198Au-colloid. 2. In all cases, including normal and cirrhotic subjects, the visualizations of spleen were seen on the scintigrams with 99mTc-Sn-colloid. In diffuse hepatic diseases, comparing both radiopharmaceuticals, the splenic accumulations were studied qualitatively and quantitatively. As the result, the ratio (spleen/liver) was thought to be useful for the differentiation of diffuse hepatic diseases concerning with splenic function and/or size. It was also shown that 99mTc-Sn-colloid was useful for a spleen scanning agent. 3. The T1/2 in the liver accumulation curves with 99mTc-Sn-colloid were not clearly differentiated in the various hepatic diseases as those with 198Au-colloid where those indexes were useful in the evaluation of liver functions. |
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| Practice | Clinical medicine |
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