Japanese
Titleオン・ライン・データ処理装置による腎のfunctional imagingに関する研究
Subtitle原著
Authors前田寿登*, 古川勇一*, 中川毅*, 山口信夫*, 田口光雄*
Authors(kana)
Organization*三重大学医学部放射線医学教室
Journal核医学
Volume12
Number4
Page341-348
Year/Month1975/8
Article原著
Publisher日本核医学会
Abstract131I-ヒップランは1回の腎循環で90%以上が尿細管細胞に選択的にとり込まれ, 尿中に分泌される. 従って, 静注投与後のdynamicsは腎血流, 尿細管機能, 腎盂尿管系の機能の判定に有用であり, 広く臨床的に用いられている. 131I-ヒップランを用いたレノグラムでは左腎および右腎それぞれの全体の機能しか表現しておらず, 腎内部の局在的な機能異常の情報を得ることは不可能である. また通常のrenal sequential imageでは, ある時間でのactivity分布を示すのみで, 経時的な各画像を比較することによって, 各領域における局所的なactivityの時間的変化を知ることは可能であるが, 定量化されておらず, 正確さに欠け, その判断に困難な場合が多い.
Practice臨床医学：一般
Keywords
English
Title"Functional Imaging" of the Kidney by Means of an On-Line Computer System
SubtitleOriginal Articles
AuthorsHisato MAEDA, Yuichi FURUKAWA, Tsuyoshi NAKAGAWA, Nobuo YAMAGUCHI, Mitsuo TAGUCHI
Authors(kana)
OrganizationDepartment of Radiology, Mie University School of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume12
Number4
Page341-348
Year/Month1975/8
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] "Functional imaging" described here is an integrated data-processing method by which regional dynamic function of an organ system can be visualized in the form of images. The joint camera-computer system used in these studies consists of a GCA-202 gamma camera and a DAP-5000N computer system. In the serial scintiphotography of the kidney, following intravenous injection of 200 - 300μCi of 131I-hippurate, 10-second frames of data in 64× 64 matrix form were acquired for a period of 20 minutes utilizing a computer system In order to decrease the statistical variation of the count, each two successive frames were summed up to reconstruct 20-second frames and thus 64×64 matrix form was converted into 32×32 matrix form. Automatic computation of six parameters, which are related to a variety of renal function, is done for each element of the latter matrix. The six parameters are : Cmax : Maximum counts. T1/2max (up) : The time interval from injection to Cmax/2. Tmax : The time interval from injection to Cmax. T1/2max (down) : The time interval from Cmax to Cmax/2. Up slope : Ratio of Cmax to Tmax. Down slope : Ratio of Cmax/2 to T1/2max (down) For each of 6 parameters, the computed values for overall matrix elements were displayed on a CRT in a 64×64 matrix form. The functional images thus obtained represent the regional dynamic function of the kidney. The images are recorded by a polaroid camera in a 128×128 matrix form. Regarding the parameters T1/2max (up) , Tmax and T1/2max (down) , time-density calibration dots were added on the same photograph for convenience in clinical evaluation, The computing time for all of these procedures is only about 2 minutes. Functional images in some illustrative cases were presented. In a patient with hydrone-phrosis, it was shown that spatial extent of delayed transport was different between accumulation phase and drainage phase. In a patient with pyelonephritis, multiple focal areas with delayed transport were shown in both accumulation phase and drainage phase. It is considered that functional imaging is of special value for the assessment of regional function of the kidney as well as other organ systems and that it will be useful for daily clinical studies, since this procedure requires only a few minutes with a computer system.
PracticeClinical medicine
Keywords

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