| Japanese |
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| Title | 肺局所133Xe洗い出し曲線の解析 - シミュレーションモデルの導入 - |
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| Subtitle | 原著 |
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| Authors | 山田公二*, 杉田実**, 岸本亮**, 目島幸子**, 木村和文***, 久住佳三*** |
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| Authors(kana) | |
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| Organization | *大阪大学医学部第一内科, **兵庫医科大学第三内科, ***大阪大学医学部中央放射線部 |
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| Journal | 核医学 |
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| Volume | 12 |
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| Number | 3 |
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| Page | 261-272 |
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| Year/Month | 1975/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「1. 緒言」肺局所における換気状態を生理的な条件下で把握することは臨床上必要であり, 従来より種々の方法で試みられてきたが, 被験者に与える苦痛や手技の煩雑さを伴い, また測定条件が必ずしも生理的な状態でなく満足しうるには至らなかった. 近年ラジオアイソトープ (以下RIと略す) の臨床的応用が急速に拡大され, 肺領域では131I-MAA, 99mTc, 133Xe等の核種が漸次利用されるに伴い, 局所レベルでの換気或は血流の機能的な解析を生理的な状態でおこないうる様になった. 著者らは, 肺領域におけるRI検査法, なかんずく133Xe法の意義を認め, シンチカメラを用いて133Xeの洗い出し曲線を計測し, シミュレーションモデルを導入し, 局所の換気機能の解明に資する方法論の確立およびその妥当性の検討を試みた. 「2. 対象, 方法および材料」 |
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| Practice | 臨床医学：一般 |
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| Keywords | |
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| English |
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| Title | A Mathematical Analysis of Regional Lung Ventilation |
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| Subtitle | Original |
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| Authors | Koji YAMADA*, Kazufumi KIMURA*, Yoshimi KUSUMI*, Minoru SUGITA**, Akira KISHIMOTO**, Sachiko MEJIMA** |
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| Authors(kana) | |
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| Organization | *Department of Medicine and Central Radiology, Osaka University Medical School, **Department of Meidicine, Hyogo Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 12 |
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| Number | 3 |
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| Page | 261-272 |
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| Year/Month | 1975/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]It is important for clinicians to estimate regional lung function under a physiological condition. Since the use of radioisotopes in investigating regional lung function, it has become easier to analyze regional ventilation and perfusion under a physiological condition. Presently it was attempted to establish a technic in studying regional lung ventilation with a mathematical analysis of the washout curve obtained after 133Xe rebreathing. In this paper a model lung has a common dead space and regional fast and slow compartments. Percent space volume and minute ventilation of each compartment were calculated by computer and compared between normal subjects and patients with pulmonary diseases. The validity for the values calculated was discussed. |
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| Practice | Clinical medicine |
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| Keywords | |
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