| Japanese |
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| Title | 57Co-BleomycinによるLung Scanの診断価値 |
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| Subtitle | 原著 |
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| Authors | 三島隆生*, 鳥住和民*, 藤野保定*, 堀啓二*, 桜井武雄**, 滝本幹之**, 前田瑞雄** |
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| Authors(kana) | |
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| Organization | *和歌山県立医大 放射線科, **胸部外科 |
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| Journal | 核医学 |
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| Volume | 12 |
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| Number | 1 |
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| Page | 7-11 |
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| Year/Month | 1975/2 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「緒言」最近, 増加の一途をたどる肺癌の診断には胸部X線写真, 断層撮影, 気管支造影等が有用であるが, これらのみでは炎症, 結核等との鑑別に困難を感じる症例が多々あり, これを補う生体侵襲の少ない補助検査法の開発が望まれている. その一翼を担うものとして, Radioisotopeを使った検査が注目を浴びているが, これには131I-MAA等を使ったorgan scanningにより, 肺病巣をcold areaとして描出する方法が現在広く一般に行われている. しかしながらこの方法は肺機能検査の意味合が強く, 腫瘍を描出するには適していない. これに対してTumorに親和性のあるR.I.を使って, これを直接描出しようとするtumor scanningが最近脚光を浴び, 131I-fibrinogen, 67Ga-citrate等の腫瘍親和性R.I.の開発, 臨床応用が進められて来た. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Experience of Lung Scans with 57Co-Bleomycin |
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| Subtitle | original |
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| Authors | Takao MISHIMA*, Yasusada FUJINO*, Keiji HORI*, Kazutami TORIZUMI*, Takeo SAKURAI**, Motoyuki TAKIMOTO**, Mizuo MAEDA** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Wakayama Medical College, **Department of Thoracic Surgery, Wakayama Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 12 |
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| Number | 1 |
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| Page | 7-11 |
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| Year/Month | 1975/2 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] It is difficult to differentiate lung cancers from lung tuberculosis, lung sarcoidosis, the other lung inflammatory disorders and benign tumors. The lung scan with 57Co-Bleomycin was suefull for the differential diagnosis in our series. In this study, 57Co-Bleomycin that we used had 5 mg of Bleomycin per 1 ml. with an activity of 1 mCi of 57Co, and were injected intravenously for 500μCi. This was rapidly eliminated through kidneys; 80% of radioactivity was found in urine in the first 24 hours as labeled Bleomycin. Therefore, the total patient irradiation is not so large. But it is important to collect and stock the urine passed during the first 24 hours. Recording were made by 5-inch crystal, 85-hole collimator 24 hours after the injection and scanning speed was 80cm/min. In our series, from January 1973 to Feburary 1974, 86 patients were studied with this method. Of these patients, 55 cases that were already confirmed by surgical operations, biopsies or autopsies, were discussed in this paper. Thirty one of 36 primary lung cancers were clearly demonstrated (86%). On the other hand, only one of 11 non-malignant lung disorders was demonstrated as hot area (9%). Therefore, for differential diagnosis of primary lung cancer scans with 57Co-Bleomycin is very usefull. We had 8 cases of metastatic lung cancers (3, from thyroid cancer; 4, from breast cancer; 1, from uterine cancer). All metastatic lung cancers from thyroid and uterine were clearly demonstrated, but from breast did not be demonstrated. Additionally, we experienced in several cases, when the lung cancers received radiation therapy, the hot areas almostly disappeared. |
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| Practice | Clinical medicine |
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| Keywords | |
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