| Japanese |
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| Title | 高齢者のCSF動態異常 (II) - 特にCSF循環遅延について - |
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| Subtitle | 原著 |
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| Authors | 山本光祥*, 千葉一夫*, 丹野宗彦*, 山田英夫*, 松井謙吉*, 飯尾正宏*, 布施正明**, 星豊**, 露無松平** |
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| Authors(kana) | |
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| Organization | *東京都養育院付属病院核医学放射線部, **東京都養育院付属病院第二診療部脳神経外科 |
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| Journal | 核医学 |
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| Volume | 11 |
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| Number | 6 |
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| Page | 625-635 |
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| Year/Month | 1974/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「はじめに」従来, 高齢者の中枢神経系の障害に関する研究は, 脳硬塞・脳出血等に関連する脳動脈硬化・脳血液循環などにむけられており, 脳脊髄液 (cerebrospinal fluid, 以下CSFと略記する) に関しては, γグロブリンの増加など, 生化学的な検討は行われているが, 加齢にともなう生理学的側面に関しては, 十分な検索が行われていない. 一方, RIを用いるCSF動態の検索はDichiroが, 1964年に発表して以来, CSF otho-rinorrhea, obstructive hydrocephalus, intraventricular tumor等の診断に広く応用されてきた. 近年, 特にnomal pressure hydrocephalus (以下NPHと略記する) の診断・手術適応の決定に重要な情報をもたらすものとして重視されている. 我々はすでに, 169Yb-DTPAによるRI cisternographyを, 高齢者を対象として実施し, その経時的イメージにより, NPHと極めて類似し, 鑑別困難な2症例を示し, CSF動態異常と高齢者に多くみられる中枢神経系の機能低下との関連を考察し報告した. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Disturbed CSF Circulation among Geriatric Patients - Significance of delayed CSF circulation - |
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| Subtitle | Original |
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| Authors | Mitsuyoshi YAMAMOTO*, Kazuo CHIBA*, Munehiko TANNO*, Hideo YAMADA*, Kengo MATSUI*, Masahiro IIO*, Masaaki FUSE**, Yutaka HOSHI**, Matsudaira TSUYUMU** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine and Radiological Science, Tokyo Metropolitan Geriatric Hospital, **Department of Surgery, Division of Neurosurgery, Tokyo Metropolitan Geriatric Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 11 |
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| Number | 6 |
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| Page | 625-635 |
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| Year/Month | 1974/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]CSF circulation have been remained to be studied in aged people. So far our results indicate the delay of CSF circulation time being correlate with deterioration' of central nervous system. RI cisternography was performed in 74 cases (45malc cares, 29 female cases, with an average age of 66) with 169Yb-DTPA injected into the subarachnoid space via lumbar puncture. Counts over the lumbar region, thoracic region and the head were recorded using PHO/Gamma HP γ-camera, scquentially after injection, and images of these regions were obtained. Cases with peak value of the brain counts after 24hours are considered to be the case with delayed circulation. In order to compare degree of the delay of CSF circulation with brain symptomes (mental dullness, gait disturbance, incontinence of urine, mutism), ratio of counts at 6 hours and 24 hours (C24/C6) was used. Out of 54 cases over 50 years old, 37 cases (69%) showed delayed circulation of CSF. Among them, 3cases showed transient ventricular filling, 4 cases persistent ventricular filling and 30 cases showed only delayed circulation. Cases without "brain symptome" his C24/C6 was below 0.92, however, the more the number of brain symptome increases the higher this ratio becomes. These ratios also increase with aging, In Summary, high incidence of abnormal CSF circulation was obserbed among aged patients. CFS circulation related well with the degree of disturbance in brain function. |
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| Practice | Clinical medicine |
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