| Japanese |
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| Title | γ - カメラレノグラフィーによる99mTc - (Sn) DTPAの評価 - 閉塞性腎障害と実質性腎障害の鑑別について - |
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| Subtitle | 原著 |
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| Authors | 大石幸彦***, 千葉一夫*, 松井謙吾*, 山田英夫*, 入倉英雄***, 飯尾正宏*, 南武**, 町田豊平** |
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| Authors(kana) | |
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| Organization | *東京都養育院付属病院核医学放射線部, **東京慈恵会医科大学泌尿器科教室 |
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| Journal | 核医学 |
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| Volume | 11 |
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| Number | 5 |
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| Page | 541-552 |
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| Year/Month | 1974/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「はじめに」腎機能検査用のラジオアイソトープには, 腎血漿流量(以下RPFと略)物質である131I-ヒップランが現在広く臨床的に応用されている. また, ヨードサラミン酸が糸球体浜過量(以下GFRと略)物質の代表として用いられている. しかし, 131I-ヒップランはγ-カメラレノグラフィーには必ずしも適当ではなく, ヨードサラミン酸は尿排泄が遅く, また使用される核種が131Iあるいは125Iで十分なphoton数を得ることが出来ないので必ずしも連続的γ-カメラレノグラフィーに適さない. そこで著者らは99mTc-(Sn)DTPAを腎機能検査に導入しGFR物質99mTc-(Sn)DTPAとRPF物質131I-ヒップランの両放射性医薬品を用いγ-カメラによるレノグラムおよび経時的腎イメージについて検討した. 今回は特に同一症例における99mTc-(Sn)DTPAと131I-ヒップランのγ-カメラレノグラムおよび, 経時的腎イメージについてその検査方法の特徴, 糸球体機能と尿細管機能を同時に検査することの有用性, 実質性腎障害と閉塞性腎障害の鑑別の可能性について検討した. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Evaluation of γ - Camera Renogram by 99mTc - (Sn) DTPA on the Differentiation of Obstructive and Parenchymal Renal Diseases - |
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| Subtitle | Original |
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| Authors | Yukihiko OHISHI, Kazuo CHIBA, Kengo MATSUI, Hideo YAMADA, Hideo, IRIKURA, Masahiro IIO1), Takeshi MINAMI, Toyohei MACHIDA2) |
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| Authors(kana) | |
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| Organization | 1)Department of Nuclear Medicine and Radiological Science, Tokyo Metropolitan Geriatric Hospital, 2)Department of Urology Tokyo Jikei University, School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 11 |
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| Number | 5 |
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| Page | 541-552 |
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| Year/Month | 1974/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | Two mCi of 99mTc-(Sn)DTPA and 300μCi of 131I-Hippuran were applied successively on 105 cases to evaluate their values for the γ-camera renograms. Cases are consisted of 53 males and 52 females ranging from 17 to 97 y. o. (mean 60 y. o. ). Nuclear Chicago Pho/Gamma HP was used and data are stored in the data store playback system. After the storing of about 20 min. renograms and renal images, ROI was set for the kidneys and γ-camera renograms were obtained. In general both renograms revealed good correlation though better images could be obtained by 99mTc-(Sn)DTPA. However, 99mTc-(Sn)DTPA was more sensitive to detect the abnormality in such cases as mild hydronephrosis or operated hydronephrosis who showed recovered renograms by 131I-Hippuran. Also 131I-Hippuran renogram shows occassionally obstructive pattern in cases with advanced parenchymal renal disease causing difficulty in differentiating parenchymal renal diseases from obstructive disorders. However 99mTc-(Sn)DTPA renogram showed clear-cut difference between these two disorders. Addition of renal images created further aids for the differential diagnosis. In conclusion γ-camera renograms by 99mTc-(Sn)DTPA combined with 131I-Hippuran renogram were found to be useful for differential diagnosis of obstructive, parenchymal and is chemic renal disorders. These methods, with its non-traumatic nature, are also quite useful for the diagnosis of renal disorders in cases with poor risk and in aged cases. |
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| Practice | Clinical medicine |
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