| Japanese |
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| Title | 99mTc2S7コロイド肝シンチグラフィによるび漫性肝疾患診断の可能性 |
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| Subtitle | 原著 |
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| Authors | 油野民雄, 鈴木豊, 久田欣一 |
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| Organization | 金沢大学医学部核医学教室 (主任 : 久田欣一教授) |
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| Journal | 核医学 |
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| Volume | 10 |
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| Number | 6 |
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| Page | 549-553 |
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| Year/Month | 1973/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「1. はじめに」肝シンチグラフィ用核種としての99mTc2S7コロイドは, 肝内限局性病変の検出, 脾描画, 患者への被曝量軽減など, 198Au-コロイドに比しその優秀性が認められてきた. しかし, コロイド粒子の均一性の問題や正常例でも大部分の例に脾描画所見を呈するため, 正常では脾描画所見を呈さない198Au-コロイドに比べてび漫性肝疾患判定基準としての応用に関しては問題があるとされてきた. そこで今回, 198Au-コロイドと99mTc2S7コロイドスキャン所見(特に脾影出現の程度)を対比し, 99mTc2S7コロイド肝スキャンのび漫性肝疾患に対する判定基準について検討を試みた. 「2. 対象と方法」急性肝炎2例, 慢性肝炎7例, 肝硬変13例, 原発性肝癌3例, バンチ氏症候群1例, その他肝疾患5例, 原発性肝癌以外の悪性腫瘍28例, 血液網内系疾患8例, その他5例, 計72症例を対象とし, 各々の症例に198Au-コロイド100μCi, 99mTc2S7コロイド2〜3mCi静注30〜60分後の肝シンチグラフィをそれぞれ施行. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | 99mTc2S7 colloid liver scintigraphy for the evaluation of diffuse hepatic disease |
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| Subtitle | Original |
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| Authors | Tamio ABURANO, Yutaka SUZUKI, Kinichi HISADA |
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| Authors(kana) | |
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| Organization | Department of Nuclear Medicine, School of Medicine, Kanazawa University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 10 |
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| Number | 6 |
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| Page | 549-553 |
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| Year/Month | 1973/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 99mTc2S7 colloid liver scintigraphy for the evaluation of diffuse hepatic disease has been considered to be questionable because of very frequent visualization of the spleen in most of normal cases whereas no visualization of the spleen is noticed in 198Au colloid liver scintigraphy. Therefore, the comparison of extrahepatic distribution was done on anterior liver scan between 99mTc2S7 colloid and 198Au-colloid, and the following results were obtained. [1. Degree of splenic activity]: Twenty three of 24 cases with splenic activity exceeded that of liver with 99mTc2S7 colloid showed various degrees of splenic activity with 198Au-colloid. Conversely, twenty six of 32 cases with liver activity exceeded that of spleen including no splenic visualization with 99MTc2S7 colloid did not show any splenic visualization with 198Au-colloid. Therefore, in the case of splenic activity exceeded that of liver on 99mTc2S7 colloid anterior liver scan, the splenic activity is considered to be significantly abnormal. [2. Another extrahepatic activity: bone marrow and lung.] Bone marrow activity with 99mTc2S7 colloid were obtained in 10 cases, and nine of which were cirrhosis. Lung activity was observed most frequently in cirrhosis, i.e. 85% of cirrhosis. On the other hand, it was observed less frequently in other diseases, i.e. 13-24%. This result suggests the possibility that the pulmonary reticuloendothelial activity rather than embolization of macroaggregates is participated in lung activity. From these results, 99mTc2S7 colloid is considered to be a fully applicable radionuclide of anterior liver scintigraphy for the evaluation of diffuse hepatic disease, and specific findings in cirrhosis are considered as followes, splenic activity highly exceeded that of liver, bone marrow activity and/or obvious lung activity on 99mTc2S7 colloid anterior liver scan. |
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| Practice | Clinical medicine |
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