| Japanese |
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| Title | 加令者のCSF動態異常 - NPH型を伴った症例を中心に - |
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| Subtitle | 症例報告 |
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| Authors | 山本光祥*, 千葉一夫*, 丹野宗彦*, 山田英夫*, 松井謙吾*, 露無松平**, 布施正明**, 飯尾正宏* |
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| Authors(kana) | |
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| Organization | *東京都養育院付属病院 核医学放射線部, **東京都養育院付属病院 第2診療部脳神経外科 |
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| Journal | 核医学 |
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| Volume | 10 |
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| Number | 4 |
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| Page | 413-420 |
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| Year/Month | 1973/8 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「はじめに」1957年Bellが, ラジオアイソトープを脳脊髄腔へ注入し, 髄液の動態の検査を行なって以来, この方法を用いて多くの報告がなされてきた. 本法のnormal pressure hydrocephalus(以下NPHとする)の診断に関する価値は大きく, また1970年Wagnerらが化学的に安定な169YbDTPAのcisternographyへの応用を始め, 副作用がほとんど認められない安全な検査として高く評価されてきた. 筆者らも169YbDTPAを用い, おもに加令者を対象」としてR. I. cisternographyを施行し, 臨床的にNPHと診断しがたい老人について, 本法により脳脊髄液の動態異常を示す2例を経験したので報告する. 「対象および方法」<対象>東京都養育院付属病院の開院以来約8カ月間の入院, 外来患者あわせて20人(男14名, 女6名), 年令は31歳から84歳までで, 平均年令は67歳である. <方法>196YbDTPA 1mCiを腰椎穿刺により脳脊髄腔へ注入し, 3, 6. 24時問後, 以後は症例に応じて延長し, PHO/GAMMA HP scinticamera(Nuclear chicago社製)を用いてその動態を記録することにより, R. I. cisternographyを施行した. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Disturbed CSF circulation among geriatric patients - Cases with normal pressure hydrocephalus pattern cisternography - |
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| Authors | Mitsuyoshi YAMAMOTO*, Kazuo CHIBA*, Munehiko TANNO*, Hideo YAMADA*, Kengo MATSUI*, Masahiro IIO*, Masaaki FUSE**, Matsudaira TSUYUMU** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine and Radiological Science, Tokyo Metropolitan Geriatric Hospital, **Department of Surgery, Division of Neurosurgery, Tokyo Metropolitan Geriatric Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 10 |
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| Number | 4 |
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| Page | 413-420 |
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| Year/Month | 1973/8 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | Two cases are reported who showed normal pressure hydrocephalus (NPH) pattern cisternography in spite of the lack of suspect of this disorders. Seventy six y. o. male case, who was diagnosed as TIA (transient ischemic attack) at 60 y. o. , 62 y. o. ,69 y. o. and 75 y. o. , was admitted to the hospital. Frequent TIA caused mental disturbance, hemiplegia and hemiparesis with a day to 10 days duration and accompanied by rapid recovery. Radioisotope cisternography revealed visualization of lateral ventricle at 3 & 5 hours after intrathecal injection of 1mCi of 169YbDTPA. Delayed absorption of 169YbDTPA was also observed. Seventy two y. o. male, who was admitted by gait disturbance with mild memory disturbance , was exalnined by RI cisternography. As is shown in Fig-2, this case revealed markedly enlarged leteral ventriclar filling at 3 & 6 hours after injection and delayed absorption of the label. Among 20 cases examined at our Hospital (14 male cases, 6 female cases, with average age of 67) 6cases (30%) were diagnosed as NPH, 4 cases (20%) showed delayed absorption of CSF, 2 cases (10%) had blockage of CSF in the spine and only 7 cases (35%) showed normal CSF circulation. This relatively high incidence of NPH pattern cisternography is considered to be quite important to treat high incidence of mental disturbances among aged populations. Our cases are quite different in clinical syndrome from those reported by Adams in 1965 who initiated the concept of NPH. In Summary, after the initial trial of radioisotope cisternography among aged population, relatively high indicence of NPH pattern cisternography was proved by this method. Especially it is important to find this disorders among cases who present little doubt on the presence of NPH. |
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| Practice | Clinical medicine |
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