| Japanese |
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| Title | Scintillation cameraによるmeningiomaとglioblastomaの鑑別診断 |
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| Subtitle | 原著 |
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| Authors | 松本皓, 中山博雅, 石光宏, 鈴木健二, 西本詮 |
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| Organization | 岡山大学脳神経外科 |
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| Journal | 核医学 |
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| Volume | 10 |
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| Number | 4 |
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| Page | 397-404 |
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| Year/Month | 1973/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「はじめに」脳シンチグラフィは, 1948年Mooreによって始められ, 主として脳腫瘍の診断を目的として発展し, 今日では臨床面における重要なスクリーニング検査の一つとしてその地位を確立している. この脳シンチグラフィは, 検査に際し副作用や合併症を伴うことがなく, 外来患者にも容易に施行でき, 次に行なうべき検査法を選択決定する上で有用なものである. さらに近年, シンチレーションカメラの導入により短時間にシンチグラムを得ることが可能となったため, 時間をおって反復検査することにより, 脳腫瘍の組織学的性状をも本法から推察しようとする試みもなされている. なかでもmeningiomaとglioblastomaはともに脳シンチグラム上, 陽性率の高いものであるが, 予後が大きく異なるため, 両者の術前鑑別診断は重要である. そこで, 本論文では, 私共の教室でこれまで手術により組織像を確認した脳腫瘍症例, とくにmeningiomaとglioblastomaの症例を中心に, 術前, シンチグラムが腫瘍の組織学的性術の鑑別診断にどの程度まで役立ったかという点について検討し, 若干の文献的考察を加え報告する. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | The Application of a Scintillation Camera for Differential Diagnosis of Meningioma and Glioblastoma |
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| Subtitle | Original |
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| Authors | Akira MATSUMOTO, Hiromasa NAKAYAMA, Hiroshi ISHIMITSU, Kenji SUZUKI, Akira NISHIMOTO |
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| Organization | Department of Neurological Surgery Okayama University Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 10 |
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| Number | 4 |
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| Page | 397-404 |
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| Year/Month | 1973/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] For neurosurgeons, it is very important to differentiate meningioma from glioblastoma before craniotomy, because the medical treatment and the prognosis of these tumors are puite different. There have been many reports on attempts to use brain scintigraphy as a means of diagnosing these tumors correctly, but these reports do not take up to what extent this method is valuable before an operation. The purpose of this report, therefore, is to review our experience of using this method on patients suspected of one of these tumors from the results of carotid angiography. As radiopharmaceutical, Tc-99 m-pertechnetate was injected intravenously and scintiphotos of the head were taken by a scintillation camera at 5, 30 and 90 minutes after injection. In meningioma, we had the highest uptake of radioisotopes at 5 minutes after injection, and the tumor appeared round, homogeneous and clearly bordered. In the case of glioblastoma, the uptake of radioisotopes increased with time, and the tumor showed an irregular, uneven and blurred form. As a result, we have correctly diagnosed 75% of meningiomas (12 out of 16 cases) and 73.9% of glioblastomas) 17 out of 23 cases). Thus, it might be concluded that sequential brain scintigraphy is clinically valuable as a method for the differentiation of meningioma from glioblastoma in cases which can hardly be diagnosed by carotid angiography. |
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| Practice | Clinical medicine |
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