| Japanese |
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| Title | 加令者の骨シンチグラム (1) 99mTcポリりん酸による骨シンチグラム |
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| Subtitle | 原著 |
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| Authors | 山本光祥***, 千葉一夫*, 丹野宗彦***, 山田英夫*, 松井謙吾*, 山田良之助**, 飯尾正宏* |
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| Organization | *東京都養育院付属病院核医学放射線部, **東京慈恵会医科大学第2内科 |
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| Journal | 核医学 |
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| Volume | 9 |
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| Number | 6 |
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| Page | 561-568 |
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| Year/Month | 1972/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「はじめに」高令者には, いわゆる骨粗鬆症が多くみられ, 又動脈壁・気管枝壁などへのカルシウム沈着などとも関連し, 加令に伴う骨代謝は重要な課題である. 骨シンチグラムとX線写真により代謝, 形態, 両面より老人性骨疾患を眺めることが可能である. 骨シンチグラム検査を行なえば, X線検査で診断が不可能な時点, 又X線的に疑わしい時点で, 骨腫瘍, 骨転移悪性腫瘍, 骨髄炎, リンパ腫, ページェット氏病などの骨疾患においても, 陽性の所見が得られるとされている. 在来のX線診断法で検出診断しうるのは, 骨カルシウム含量に30〜50%に及ぶ変化が生じたときであって, 早期診断は難しい. 全身スキャンニング法も普及してきており, 骨スキャンの重要性は今後増加するものと思われる. 現在, 各種の骨RIスキャンニング法が試みられているが, 核種の選定上, 99mTcがシンチグラフィーに最も適しているRIとされており, 99mTcを用いた骨シンチグラム検査の実現は, 待望されていたものである. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Bone scintigraphy of the aged patient (1) 99mTc - polyphosphate bone scintigraphy |
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| Authors | Mitsuyoshi Yamamoto, Kazuo Chiba, Munehiko Tanno, Hideo Yamada, Kengo Matsui, Ryonsuke Yamada, Masahiro Iio |
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| Organization | Tokyo Metropolitan Geriatric Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 9 |
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| Number | 6 |
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| Page | 561-568 |
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| Year/Month | 1972/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | Application and evaluation of new bone seeking radiopharmaceutical, 99mTc-polyphosphate were reported here. Also analysis of image by digital color display data amalyzer(Phosdac)was performed. The subjects of study are cases at Tokyo metropolitan Geriatric Hospital ranging from 63-85 years old, with several kinds of bone diseases. Polyphosphate kits(Diagnostic Isotopes Inc. )were used to prepare 99mTc label and Pho/gamma HPγ-camera was used for scintigraphy. The images obtained were further analyzed by Phosdac to obtain clear image of the bone system. In the final preparation, presence of approximately 30%of free 99mTc was noticed by paperchromatography. 99mTc-p. p. was cleared from the blood with half time of about 60 minites. Urinary excretion is proved to be 40-60%within 24 hrs. Bone system was visualized rather clearly with high accmulation of the label to the diseased region in spite of the fact that geriatric cases had marked general osteoporotic tendencies. In some cases ribs were clearly visualized and different information from that of X-ray was obtained by scanning images. Data processing by Phosdac increased diagnostic accuracy by enhancing the difference of the density of the image as well as eliminating the background caused by free 99mTcO4. In conclusion 99mTc-polyphosphate was proved to be useful for bone scanning in geriatric cases. Digital color display data analyzer was successfully applied for the processing of the original data. |
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| Practice | Clinical medicine |
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