| Japanese |
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| Title | 113mInによる頭蓋内疾患の診断 (形態および動態からの診断) |
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| Subtitle | 原著 |
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| Authors | 今枝孟義*, 仙田宏平*, 坂田一記**, 山田弘**, 田中千凱** |
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| Authors(kana) | |
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| Organization | *岐阜大学 放射線科, **第2外科 |
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| Journal | 核医学 |
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| Volume | 9 |
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| Number | 1 |
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| Page | 39-64 |
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| Year/Month | 1972/2 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. 緒言」1885年P.Ehrlichは, 酸性色素coerulein-Sを動物に静注したところ, 他のすべての臓器が色素によってよく染るにもかかわらず脳のみが染らないのを認めた. 更にE.E.Goldmanは, trypan blueを直接髄液内に注入したところ, 動物は痙攣と麻痺を起して多くは死の転帰をとるのに反し, 静脈内に注入した場合はその10倍量を注入しても何ら症状を呈さなかったと言う. これらの実験より, 髄液から脳へはほとんど選択性がなく色素の通過を許すが, 血液から脳へは選択性があり, 脳自体が防御機構を備えていることを想定させ, 1921年L.Stern, 1933年F.K.Walterらは, これについて血液・脳関門という概念を初めて提唱した. また1940年T.Bromanは, 正常脳組織内に入りこまないtrypan blueが脳腫瘍などの病巣部を濃染することを認め, 血液・脳関門の破壊によって病巣部に色素が入りこむことをみつけた. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | Diagnosis of Intracranial Diseases with 113mIn (Formal and Dynamic Diagnosis) |
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| Subtitle | |
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| Authors | Takeyoshi IMAEDA*, Kouhei SENDA*, Kazuki SAKATA**, Hiromu YAMADA**, Sengai TANAKA** |
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| Authors(kana) | |
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| Organization | *Deportment of Radiology, School of Medicine, Gifu University, **Second Department Surgery, School of Medicine, Gifu University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 9 |
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| Number | 1 |
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| Page | 39-64 |
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| Year/Month | 1972/2 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] We performed the brain scintigraphy on 270 cases of the intracranial diseases and the suspected patients with 131mIn Fe compound. Out of them, on 101 cases, which were pathologically and histologically proven to be tumor (in the above diagnosis), we made further examinations in order to investigate on the possibility of the differerentiation of tumors by the formal and dynamic patterns observed. The formal pattern was got from the photo-scintigram and the dynamic pattern from the time histogram which was obtained by using the Data-store play-back system and the Rate-meter. We classfied the above 101 cases into Neoplasm (77 cases) and Nonneoplasm (24 cases) and studied on each case, the rate of interpretation of diseases, form of abnormal portion, contours of abnormal portion, ratio of RI concentration on the abnormal portion to that on the nomal portion, successive RI dynamic change within the abnormal portion, etc. Thus, our several knowledges which appear in our report on the discrimination of brain tumors by the scintigram were obtained. |
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| Practice | Clinical medicine |
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| Keywords | |
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