| Japanese |
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| Title | 骨の悪性腫瘍, 特に転移の85Srスキャンニング |
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| Subtitle | 原著 |
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| Authors | 東浦利昌, 阿武保郎* |
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| Organization | 鳥取大学医学部放射線医学教室, *主任:教授 |
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| Journal | 核医学 |
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| Volume | 6 |
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| Number | 1 |
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| Page | 109-117 |
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| Year/Month | 1969/3 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 悪性腫瘍が血行性転移として造血骨髄を有する骨格系にしばしば生ずることは容易に考えられることであるが, 特に脊椎に転移することが多いことについては, Jaffeもそれを生理解剖学的に説明している. しかしこれをX線学的に識別することは, 骨の無機物の変化が30%以上にもならなければ困難であるといわれる. 脊椎の断層撮影では0.5cmの径以上の変化はとらえることが出来るといわれているが, 単純X線写真では2〜3cm以上にならなければわからないというものもある. したがって臨床的に脊椎転移によると思われる症状があるにもかかわらず, X線学的にそれを発見することが困難であることはよく経験することである. 癌末期の神経痛の原因としては悪性腫瘍の脊椎転移が多いが, 末期患者の苦痛をすくなくするうえでも転移巣の発見は必要である. 近年, 腫瘍の骨転移の早期発見のために, 85Srによる骨スキャンが臨床的に応用されX線学的に明らかでない時期にこれをとらえることが出来るといわれる. |
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| Practice | 臨床医学：一般 |
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| English |
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| Title | 85Sr bone scanning in the early detection of the bone malignancies, especially metastases |
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| Subtitle | |
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| Authors | Toshimasa HIGASHIURA, Y. ANNO* |
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| Authors(kana) | |
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| Organization | Departement of Radiology Tottori University School of Medicine, *Director: Prof. |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 6 |
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| Number | 1 |
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| Page | 109-117 |
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| Year/Month | 1969/3 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Abstract] The author performed 85Sr bone scanning in 75 patients with proven or suspected malignant bone lesions to evaluate this method in the early detection of bone neoplasms. After intravenous injection of 20 μCi of 85Srcl2, profile scanning was performed. Additional administration of IOO μCi in patients with p-positive profile scanning was followed by area scanning. In IO patients, scanning revealed abnormalities earlier or more extensively than those visualized by roensgenography. Negative scans were obtained in 5 patients with marked lesions of bones on roentgenograms. In a case with malignant hemaogioendothelioma of sacrum, negative scan was obtained on admission, but following radiation therapy enhanced new bone formation and positive scan was obtained according to repair of sacrum on roentgenograms. In general, 85Sr bone scanning is useful in the early detection of bone tumor in the skull, vertebra and pelvis. However, as accumulation of strontium is not specific for the malignant bone tumor, positive scan may be obtained in other conditions with possibility of new bone formation. Especially in pediatric age group, because the normal high uptake of epiphyseal bone formation may simulate positive scan, one should carefully evaluate scanograms of children with bone tumor. High exposure dose and lengthy of the procedure are disadvantages of this method, but scinticamera instead of conventional moving scanner and using short lived isotope may overcome these shortcomings. |
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| Practice | Clinical medicine |
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